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| | B-HT 920 DIHYDROCHLORIDE Basic information |
| Product Name: | B-HT 920 DIHYDROCHLORIDE | | Synonyms: | 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amineDihydrochloride,6-Allyl-2-amino-5,6,7,8-tetrahydro-4;B-HT920dihydrochlorideTalipexole;5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride;Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride;5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d] azepin-2-amine dihydrochloride;talipexole hydrochloride;6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride;2-Amino-6-allyl-4,5,7,8-tetrahydro-6H-thiazolo(5,4-D)azepin-dihydrochlorid [german] | | CAS: | 36085-73-1 | | MF: | C10H17Cl2N3S | | MW: | 282.23 | | EINECS: | | | Product Categories: | Adrenoceptor;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals | | Mol File: | 36085-73-1.mol |  |
| | B-HT 920 DIHYDROCHLORIDE Chemical Properties |
| Melting point | 245°C dec. | | storage temp. | Desiccate at RT | | solubility | H2O: >20 mg/mL | | form | solid | | color | off-white |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | RTECS | XJ7050340 |
| | B-HT 920 DIHYDROCHLORIDE Usage And Synthesis |
| Description | B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson’s disease. B-HT 920 is also an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 μM) receptors. | | Chemical Properties | B-HT 920 DIHYDROCHLORIDE is Light Yellow Solid | | Uses | B-HT 920 DIHYDROCHLORIDE is an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent | | Definition | ChEBI: Talipexole dihydrochloride is an azepine. | | Biological Activity | Dopamine D 2 receptor agonist, α 2 -adrenoceptor agonist and 5-HT 3 receptor antagonist. Displays antiParkinsonian activity. |
| | B-HT 920 DIHYDROCHLORIDE Preparation Products And Raw materials |
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