| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:c-Fms-IN-8;cFmsIN8,c Fms IN 8
CAS:1255303-58-2
Purity:98% Package:5 mg
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| Company Name: |
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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| Tel: |
021-59167510 18117107507 |
| Email: |
vip@med-life.cn |
| Products Intro: |
Product Name:c-Fms-IN-8
CAS:1255303-58-2
Purity:>=99% Package:50mg;100mg;10mg;25mg;5mg
|
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| | c-Fms-IN-8 Basic information |
| Product Name: | c-Fms-IN-8 | | Synonyms: | cFmsIN8,c Fms IN 8;Methanone, [3-[4-[(4-ethylphenyl)methoxy]-3-methoxyphenyl]-1-azetidinyl][4-(2-hydroxyethoxy)-2-pyridinyl]- | | CAS: | 1255303-58-2 | | MF: | C27H30N2O5 | | MW: | 462.54 | | EINECS: | | | Product Categories: | | | Mol File: | 1255303-58-2.mol |  |
| | c-Fms-IN-8 Chemical Properties |
| Boiling point | 671.2±55.0 °C(Predicted) | | density | 1.230±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 13.89±0.10(Predicted) |
| | c-Fms-IN-8 Usage And Synthesis |
| Description | c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].
IC50: 9.1 nM (CSF-1R)[1]. | | References | [1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118. |
| | c-Fms-IN-8 Preparation Products And Raw materials |
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