(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE

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Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: CAS:151792-53-9
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
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Products Intro: Product Name:(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
CAS:151792-53-9
Purity:99% Package:1KG;1USD
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
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Products Intro: Product Name:tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
CAS:151792-53-9
Package:1KG;25KG
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Products Intro: Product Name:(1R,4S)-TERT-BUTYL 3-OXO-2-AZABICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLATE
CAS:151792-53-9
Purity:97% HPLC Package:1g;10g;100g;1kg
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Products Intro: Product Name:(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
CAS:151792-53-9
Package:1g;5g;10g Remarks:customizable

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(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Basic information
Product Name:(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
Synonyms:(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE;(1R,4S)-tert-butyl 3-oxo-2-aza-bicyclo[2.2.1]hept-5-ene-2-carboxylate;2-Azabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-oxo-,1,1-diMethylethyl ester, (1R,4S)-;tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate;racemic-(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate*;(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester;(1R,4S)-(-)-2-tert-Butoxycarbonyl-2-azabicyclo[2.2.1]hept-5-en-3-one;2-Methyl-2-Propanyl (1R,4S)-3-Oxo-2-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxylate
CAS:151792-53-9
MF:C11H15NO3
MW:209.24
EINECS:
Product Categories:
Mol File:151792-53-9.mol
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Structure
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Chemical Properties
Melting point 85.0-86.5 °C
Boiling point 339.8±31.0 °C(Predicted)
density 1?+-.0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka-2.32±0.20(Predicted)
Safety Information
MSDS Information
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Usage And Synthesis
Uses(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing ent-Abacavir (Abacavir EP Impurity A) (A105015), an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Preparation Products And Raw materials
Preparation Products(1S-cis)-4-Amino-2-cyclopentene-1-methanol-->(S)-4-((tert-butoxycarbonyl)amino)cyclopent-1-enecarboxylic acid
Tag:(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE(151792-53-9) Related Product Information
tert-butyl (3aS,6aR)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,3a,4,6a-tetrahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 3-N-Boc-Cis-Tetrahydrofuran-3,4-Diamine tert-butyl (3aR,5s,6aS)-5-(hydroxymethyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate exo-3-Boc-3-azabicyclo[3.1.0]hexane-6-methanol Carbamic acid, [(3S,4S)-4-aminotetrahydro-3-furanyl]-, 1,1-dimethylethyl ester tert-butyl ((3S,4S)-4-aminotetrahydrofuran-3-yl)carbamate rel tert-butyl ((3R,4R)-4-hydroxytetrahydro-2H-pyran-3-yl)carbamate tert-Butyl 5-(hydroxymethyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate rel-(3r,4r)-3-(boc-amino)-5-fluoropiperidine (2S,4R)-4-hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester tert-butyl ((3R,4R)-4-aminotetrahydrofuran-3-yl)carbamate N-BOC-(3S,4S)-3,4-PYRROLIDINEDIOL tert-butyl (3S)-3-(hydroxymethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate tert-butyl (3R,4S)-3-amino-4-methylpyrrolidine-1-carboxylate tert-butyl (3R)-3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxyla (R)-1-BOC-3-(Hydroxymethyl)piperazine tert-butyl (3aR,7aS)-6-oxohexahydropyrano[3,4-c]pyrrole-2(3H)-carboxylate tert-butyl (3aR,5s,6aS)-5-cyanohexahydrocyclopenta[c]-pyrrole-2(1H)-carboxylate