L-3-(3,4-二羟基苯基)-2-甲基丙氨酸盐酸盐
| 中文名称 | L-3-(3,4-二羟基苯基)-2-甲基丙氨酸盐酸盐 |
|---|---|
| 中文同义词 | L-3-(3,4-二羟基苯基)-2-甲基丙氨酸盐酸盐;化合物 T15701 |
| 英文名称 | L-(-)-α-Methyldopa (hydrochloride) |
| 英文同义词 | L-(-)-α-Methyldopa (hydrochloride);MK-351 hydrochloride;L-(-)-&3-hydroxy-a-methyl- L-Tyrosine hydrochloride;L-(-)- Alpha -Methyldopa hydrochloride;(-)-α-Methyldopa Hydrochloride;L-(-)-α-Methyldopa hydrochloride |
| CAS号 | 884-39-9 |
| 分子式 | C10H14ClNO4 |
| 分子量 | 247.68 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 884-39-9.mol |
| 结构式 |  |
L-3-(3,4-二羟基苯基)-2-甲基丙氨酸盐酸盐 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 粉末 |
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) 是一种 α-肾上腺素能激动剂（对 α2-adrenergic receptors 有选择性）。Methyldopa hydrochloride 是一种前药，在中枢神经系统中被代谢 (α-Methylepinephrine)。
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.
| Animal Model: | 60-day-old male rats |
| Dosage: | 200 mg/kg |
| Administration: | I.p. |
| Result: | Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration. |