2-甲基硫代二磷酸腺苷
中文名称 | 2-甲基硫代二磷酸腺苷 |
---|---|
中文同义词 | 化合物 T23581 |
英文名称 | 2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTH |
英文同义词 | 2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTH;2-(methylthio)adenosine 5'-diphosphate trisodium salt;2-(Methylthio)adenosine 5′-diphosphate trisodium salt hydrate,2-(Methylthio)adenosine 5′-trihydrogen diphosphate trisodium salt hydrate, 2-Methylthio-ADP trisodium salt hydrate;2-(Methylthio)adenosine 5′-diphosphate trisodium salt hydrate;2-(Methylthio)adenosine 5′-trihydrogen diphosphate trisodium salt hydrate;2-Methylthio-ADP trisodium salt hydrate;2-Methylthioadenosine diphosphate (sodium salt);2-Methylthioadenosine diphosphate |
CAS号 | 475193-31-8 |
分子式 | NULL |
分子量 | 0 |
EINECS号 | |
相关类别 | 制剂-激动剂 |
Mol文件 | 475193-31-8.mol |
结构式 |
2-甲基硫代二磷酸腺苷 性质
储存条件 | -20°C |
---|---|
溶解度 | H2O:>20mg/mL |
形态 | 粉末 |
颜色 | 白色 |
水溶解性 | Water: soluble |
2-Methylthioadenosine diphosphate trisodium (2-Methylthio-ADP trisodium) 是一种有效的嘌呤能 P2Y 受体激动剂,对人 P2Y13、小鼠 P2Y13 和人 P2Y12 的 EC50 分别为 19、6.2 和 5 nM。2-Methylthioadenosine diphosphate trisodium 对人 P2Y1 和大鼠 P2Y6 的 pEC50 分别为 8.29 和 5.75。2-Methylthioadenosine diphosphate trisodium 诱导血小板聚集和形态改变,并抑制前列腺素E1作用下血小板内环腺苷酸的积累。
2-Methylthioadenosine diphosphate trisodium (2-Methylthio-ADP trisodium) is a powerful aggregating agent for human platelets. 2-Methylthioadenosine diphosphate trisodium is also a powerful inhibitor of the accumulation of cyclic AMP in intact platelets exposed to PGE1 and a phosphodiesterase inhibitor.