| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.com |
| Products Intro: |
Product Name:ADTL-SA1215
CAS:782387-91-1
Purity:详情请点击官网 Package:1 mg
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| | Methanone, (2-butyl-3-benzofuranyl)[3,5-diiodo-4-[3-(1-pyrrolidinyl)propoxy]phenyl]- Basic information |
| | Methanone, (2-butyl-3-benzofuranyl)[3,5-diiodo-4-[3-(1-pyrrolidinyl)propoxy]phenyl]- Chemical Properties |
| Boiling point | 661.3±55.0 °C(Predicted) | | density | 1.614±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 10.10±0.20(Predicted) |
| | Methanone, (2-butyl-3-benzofuranyl)[3,5-diiodo-4-[3-(1-pyrrolidinyl)propoxy]phenyl]- Usage And Synthesis |
| Biological Activity | ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative breast cancer. | | References | [1]. Zhang J, et al. Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14192-14216. |
| | Methanone, (2-butyl-3-benzofuranyl)[3,5-diiodo-4-[3-(1-pyrrolidinyl)propoxy]phenyl]- Preparation Products And Raw materials |
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