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Product Name:2-Amino-3-cyanopropanoicacid CAS:923-01-3 Purity:97% Package:1g;5g;10g;25g;50g;100g;250g;500g;1kg;5kg;10kg;25kg;50kg;100kg;250kg;500kg
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| 3-cyanoalanine Basic information |
Product Name: | 3-cyanoalanine | Synonyms: | 3-cyanoalanine;2-Amino-3-cyanopropanoic acid;3-Cyano-2-aminopropionic acid;Alanine, 3-cyano- | CAS: | 923-01-3 | MF: | C4H6N2O2 | MW: | 114.1 | EINECS: | | Product Categories: | | Mol File: | 923-01-3.mol | |
| 3-cyanoalanine Chemical Properties |
Boiling point | 213.59°C (rough estimate) | density | 1.3565 (rough estimate) | refractive index | 1.4487 (estimate) |
| 3-cyanoalanine Usage And Synthesis |
Definition | ChEBI: 3-cyanoalanine is an alanine derivative obtained by replacement of one of the methyl hydrogens in alanine with a cyano group It is an alanine derivative, an aliphatic nitrile and a non-proteinogenic alpha-amino acid. | Synthesis Reference(s) | Tetrahedron, 22, p. 2303, 1966 DOI: 10.1016/S0040-4020(01)82149-9 | Metabolism | In the living plant, 3-cyanoalanine is mainly bound as its gama-glutamyl derivative. The enzyme, beta-cyanoalanine synthase, catalysing the reaction between cysteine and cyanide has been isolated from seedlings of the blue lupin (Lupinus angustifolius, Leguminosae).
3-Cyanoalanine is a neurotoxin, causing convulsions and muscular rigidity in rats and chicks. In rats, the compound also causes cystathioninuria, the lethai dose being 20mg/100g body weight. This metabolic defect can be prevented by injection of pyridoxal phosphate. Thus, beta-cyanoalanine interferes with pyridoxal metabolism and inhibits the enzyme gama-cystathionase.
In non-accumulating plants, 3-cyanoalanine is enzymatically hydrolysed to the protein amino acid, asparagine, by 3-cyanoalanine hydrolase. Thus, this nonprotein amino acid could be a ubiquitous constituent of plants, but may only accumulate in those species whieh do not contain 3-cyanoalanine hydrolase. |
| 3-cyanoalanine Preparation Products And Raw materials |
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