Bis-peg10-nhs ester
中文名称 | Bis-peg10-nhs ester |
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中文同义词 | 琥珀酰亚胺酯-十聚乙二醇-琥珀酰亚胺酯 |
英文名称 | Bis-peg10-nhs ester |
英文同义词 | 4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid, 1,34-bis(2,5-dioxo-1-pyrrolidinyl) ester;Di-NHS Ester-PEG10 |
CAS号 | 2221949-02-4 |
分子式 | C32H52N2O18 |
分子量 | 752.76 |
EINECS号 | |
相关类别 | |
Mol文件 | 2221949-02-4.mol |
结构式 |
Bis-peg10-nhs ester 性质
PEGs
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Alkyl/ether
|
Cleavable
|
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.