| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Complement C4
CAS:80295-48-3
Purity:main >= 300,000C4H50 units/mg protein Package:0.1mg Remarks:C8195
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| | C4, HUMAN Basic information |
| | C4, HUMAN Chemical Properties |
| storage temp. | −70°C | | form | Liquid |
| Hazard Codes | B | | WGK Germany | 2 |
| | C4, HUMAN Usage And Synthesis |
| Uses | Complement C4 from human serum has been used in mannose binding lectin (MBL) complex assay of serum samples and in MBL-associated serine proteases based C4 activation assay of plasma samples. | | General Description | Complement C4 is mapped to human chromosome 6p21.33. It exists in two isoforms as c4A and c4B. C4 is a 200 kDa protein belonging to α2 macroglobulin (α2M) family. It undergoes posttranslational modification like sulfation and glycosylation and finally proteolysis to become a mature protein. | | Biochem/physiol Actions | Variation in the copy number of the complement C4 gene alters the complement c4A and c4B levels in age-related macular degeneration (AMD) and increases risk of developing schizophrenia. |
| | C4, HUMAN Preparation Products And Raw materials |
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