印楝沙兰林
| 中文名称 | 印楝沙兰林 |
|---|---|
| 中文同义词 | 化合物 T34488 |
| 英文名称 | SALANNIN(P) |
| 英文同义词 | SALANNIN(P);2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-(((2E)-2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2ar,3R,5S,5ar,6R,6ar,8R,9ar,10as,10br,10cr)-;2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-((2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2aalpha,3beta,5beta(E), 5aalpha,6alpha,6aalpha,8beta,9abeta,10aalpha,10balpha,10cbeta)-(+)-;Azadirachtin, neem;Azadriactin;Caswell no. 594a;Margosan-o-concentrate;2H,3H-Cyclopenta[b]furo[2',3',4':4,5]naphtho[2,3-d]furan-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2a,4,5,5a,6,6a,8,9,9a,10a,10b,10c-dodecahydro-2a,5a,6a,7-tetramethyl-5-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-, methyl ester, (2aR,3R,5S,5aR,6R,6aR,8R,9aR,10aS,10bR,10cR)- |
| CAS号 | 992-20-1 |
| 分子式 | C34H44O9 |
| 分子量 | 596.713 |
| EINECS号 | |
| 相关类别 | 中药对照品;对照品-标准品;Limonoids (Citrus, Bitter Compounds) |
| Mol文件 | 992-20-1.mol |
| 结构式 |  |
印楝沙兰林 性质
| 熔点 | 167～170℃ |
|---|---|
| 沸点 | 631.9±55.0 °C(Predicted) |
| 密度 | 1.24±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 可溶于氯仿（少许）、甲醇（少许） |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| LogP | 5.560 (est) |
| EPA化学物质信息 | Salannin (992-20-1) |
Salannin，一种柠檬苦素，具有抗溃疡和杀精活性。Salannin 对革兰氏阳性菌和革兰氏阴性菌均有抗菌活性。
Salannin (10, 20, 50 mg/kg; p.o.) shows a significant protective activity on Aspirin (HY-14654) induced gastric lesions.
| Animal Model: | Wistar rats, weighing 200-220 g (acetyl salicylic acid induced gastric lesions) |
| Dosage: | 10, 20 and 50 mg/kg |
| Administration: | P.o. |
| Result: | Significantly and dose dependently inhibited acetyl salicylic acid-induced gastric lesions. |