|
| Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis- Basic information |
| Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis- Chemical Properties |
Boiling point | 234.0±33.0 °C(Predicted) | density | 0.90±0.1 g/cm3(Predicted) |
| Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis- Usage And Synthesis |
Uses | The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from a cis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexanol allows for the straightforward application in organic synthesis, after simple deprotection. It can be utilized to prepare fluorinated analogues of known compounds. |
| Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis- Preparation Products And Raw materials |
|