Β-酪啡肽-7
| 中文名称 | Β-酪啡肽-7 |
|---|---|
| 中文同义词 | Β-酪啡肽-7;婴儿猝死综合征/酪啡肽Β/-CASOMORPHIN抗体;化合物Β-CASOMORPHIN, BOVINE(2TFA);Β-CASOMORPHIN-7 (BOVINE); BOVINE Β-CASOMORPHIN-7;Β-酪啡肽-7;Β-酪啡肽,牛 |
| 英文名称 | BETA-CASOMORPHIN (BOVINE) |
| 英文同义词 | H-TYR-PRO-PHE-PRO-GLY-PRO-ILE-OH;BETA-CASOMORPHIN-7;BETA-CASOMORPHIN-7 (BOVINE);BETA-CASOMORPHIN-7 (BOVINE) 4H2O;BETA-CASOMORPHIN (BOVINE);BETA-CASOMORPHIN (1-7), BOVINE;BETA CASOMORPHIN;L-TYR-PRO-PHE-PRO-GLY-PRO-ILE |
| CAS号 | 72122-62-4 |
| 分子式 | C41H55N7O9 |
| 分子量 | 789.92 |
| EINECS号 | |
| 相关类别 | 多肽;标准品;peptide |
| Mol文件 | 72122-62-4.mol |
| 结构式 |  |
Β-酪啡肽-7 性质
| 储存条件 | -15°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
IC50: 14 μM (Opioid receptor)
β-Casomorphin, bovine (0.1 μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment.
β-Casomorphin, bovine (0.1 μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels.
β-Casomorphin, bovine do not modify the expression of rMuc1, rMuc4, and rMuc5AC.
β-Casomorphin, bovine (0.1 μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).
β-Casomorphin, bovine (7.5×10
−6
mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats.
β-Casomorphin, bovine (7.5×10
−6
mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats.
β-Casomorphin, bovine (7.5×10
−6
mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats.
β-Casomorphin, bovine (7.5×10
−6
mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.
| Animal Model: | Male Sprague-Dawley (SD) rats (200 g±10 g) |
| Dosage: | 7.5×10 −6 mol/day/kg |
| Administration: | Oral gavage; for 30 days |
| Result: | Increased plasma insulin and decreased plasma glucagon of diabetic rats. |
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-P0179 | Β-酪啡肽-7 β-Casomorphin, bovine | 72122-62-4 | 5mg | 800元 |
| 2024/04/30 | HY-P0179 | Β-酪啡肽-7 β-Casomorphin, bovine | 72122-62-4 | 10mg | 1400元 |