LYS-PHE-ILE-GLY-LEU-MET-NH2
| 中文名称 | LYS-PHE-ILE-GLY-LEU-MET-NH2 |
|---|---|
| 中文同义词 | 化合物ELEDOISIN RELATED PEPTIDE;ELEDOISIN相关肽;ELEDOISIN-RELATED PEPTIDE 三氟乙酸盐;ELEDOISIN-RELATED PEPTIDE TFA;ELEDOISIN RP|||ELEDOISIN-RELATED PEPTIDE|||ELEDOISIN RELATED PEPTIDE(2TFA) |
| 英文名称 | ELEDOISIN-RELATED PEPTIDE |
| 英文同义词 | H-LYS-PHE-ILE-GLY-LEU-MET-NH2;ELEDOISIN-RELATED PEPTIDE;L-LYS-PHE-ILE-GLY-LEU-MET NH2;LYS-PHE-ILE-GLY-LEU-MET-NH2;LYS-PHE-ILE-GLY-LEU-MET-NH2 2ACOH 3H2O;(2S)-2,6-bis(azanyl)-N-[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl]amino]-4-methyl-1-oxo-pentan-2-yl]amino]-2-oxo-ethyl]amino]-3-methyl-1-oxo-pentan-2-yl]amino]-1-oxo-3-phenyl-propan-2-yl]hexanamide;(2S)-2,6-diamino-N-[(1S)-1-(benzyl)-2-[[(1S,2S)-1-[[2-[[(1S)-1-[[(1S)-1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]amino]-2-keto-ethyl]carbamoyl]-2-methyl-butyl]amino]-2-keto-ethyl]hexanamide;(2S)-2,6-diamino-N-[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide |
| CAS号 | 2990-43-4 |
| 分子式 | C34H58N8O6S |
| 分子量 | 706.94 |
| EINECS号 | |
| 相关类别 | Peptide |
| Mol文件 | 2990-43-4.mol |
| 结构式 |  |
LYS-PHE-ILE-GLY-LEU-MET-NH2 性质
| 熔点 | 244-245 °C |
|---|---|
| 沸点 | 1083.4±65.0 °C(Predicted) |
| 密度 | 1.166±0.06 g/cm3(Predicted) |
| 储存条件 | -15°C |
| 溶解度 | 可溶于水 |
| 形态 | 固体 |
| 酸度系数(pKa) | 13.37±0.46(Predicted) |
Eledoisin Related Peptide是物质P的类似物，刺激神经元并触发行为反应。它也是 tachykinin receptor 的配体。
Tachykinin receptor
Eledoisin Related Peptide shares with Substance P (SP) a common N-terminal amino acid sequence and has been shown by to have SP-like activity in the periphery (gut and salivary glands) and the CNS. Eledoisin-related peptide seems to be roughly equipotent with Substance P at identical ejection currents on the single-cell activity of neurons in this nucleus. Both glutamate and substance P (and its analogue, eledoisin-related peptide) have excitatory effects on the activity of respiratory neurons and reflex interneurons.
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