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Twochem Co.Ltd.
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021-58111628 15800915896 |
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Products Intro: |
Product Name:ST3932 CAS:1246018-21-2 Purity:98%+ Package:0.1g;1g;5g
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Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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sales@dcchemicals.com |
Products Intro: |
Product Name:ST3932 CAS:1246018-21-2 Purity:98% HPLC Package:100mg,250mg,1g
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Company Name: |
cjbscvictory
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13348960310 13348960310 |
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3003867561@qq.com |
Products Intro: |
Product Name:ST3932 CAS:1246018-21-2 Purity:98% Package:5mg;10mg;20mg;50mg;100mg;200mg
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Product Name: | ST3932 | Synonyms: | ST3932;ST-3932,ST3932;9H-Purine-2-propanol, 6-amino-α,9-dimethyl-8-(2H-1,2,3-triazol-2-yl)- | CAS: | 1246018-21-2 | MF: | C12H16N8O | MW: | 288.32 | EINECS: | | Product Categories: | | Mol File: | 1246018-21-2.mol | |
| ST3932 Chemical Properties |
Boiling point | 482.7±55.0 °C(Predicted) | density | 1.62±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | pka | 14.96±0.20(Predicted) |
| ST3932 Usage And Synthesis |
Description | ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. ST3932 inhibits agonist-induced cAMP accumulation with an IC50 value of 450 nM[1]. ST3932 (10, 20, 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in mice. ST3932 (20, 40 mg/kg, i.p.) significantly increases the number of contralateral turns induced by l-DOPA in rats[1]. | References | [1]. ST3932, et al. Animal models of Parkinson?s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535). Eur J Pharmacol. 2015 Aug 15;761:353-61. |
| ST3932 Preparation Products And Raw materials |
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