噻哌溴铵
| 中文名称 | 噻哌溴铵 |
|---|---|
| 中文同义词 | 3-(二噻吩-2-基亚甲基)-5-甲氧基-1,1-二甲基-1-哌啶溴化物;噻哌溴铵;化合物 T12825 |
| 英文名称 | Timepidium bromide |
| 英文同义词 | TIMEPIDIUM BROMIDE;TIMEPIDIUM;1,1-Dimethyl-5-methoxy-3-(dithien-2-ylmethylene)piperidinium bromide;Mepidium;Piperidinium, 3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethyl-, bromide (9CI);SA 504;SA 50Y;Sesden |
| CAS号 | 35035-05-3 |
| 分子式 | C17H22BrNOS2 |
| 分子量 | 400.4 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 35035-05-3.mol |
| 结构式 |  |
噻哌溴铵 性质
| 熔点 | 198-200° |
|---|---|
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
Timepidium bromide (Sesden; SA504) 是一种抗胆碱剂。
Cholinergic
Effects of Timepidium bromide (TB), acetylcholine (ACh) and neostigmine (Neost) on gastric and duodenal blood flow distribution are studied by the use of 131 I-labeled macroaggregated human serum albumin (MAA) in rabbits. In normal rabbits, gastric blood flow is found to be uneven in various regions of the stomach: anterior corpus (50% of total gastric blood flow) greater than posterior corpus (40%) greater than pyloric antrum (7%). Intravenous administration of Timepidium bromide (200 μg/kg) to normal rabbits produces a slight increase in total gastric blood flow, but the increase in the mucosal layer of the pyloric antrum is considerable.