Thiol-dPEG4-amie manufacturers
- Thiol-PEG3-NH2
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- $0.00 / 500mg
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2024-03-27
- CAS:1189760-69-7
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
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| | Thiol-dPEG4-amie Basic information |
| Product Name: | Thiol-dPEG4-amie | | Synonyms: | Thiol-dPEG4-amie;HS-PEG3-CH2CH2NH2·HCl;Thiol-PEG4-amine;Thiol-PEG3-NH2;2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethane-1-thiol;Amino-PEG4-Thiol;Ethanethiol, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]- | | CAS: | 1189760-69-7 | | MF: | C8H19NO3S | | MW: | 209.31 | | EINECS: | | | Product Categories: | | | Mol File: | 1189760-69-7.mol |  |
| | Thiol-dPEG4-amie Chemical Properties |
| Boiling point | 309.6±32.0 °C(Predicted) | | density | 1.060±0.06 g/cm3(Predicted) | | pka | 9?+-.0.10(Predicted) |
| | Thiol-dPEG4-amie Usage And Synthesis |
| Biological Activity | HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Thiol-dPEG4-amie Preparation Products And Raw materials |
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