| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:TMP780;TMP780,TMP-780
CAS:1422053-03-9
Purity:98% Package:10 mg;100 mg;25 mg;50 mg
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| Company Name: |
RD International Technology Co., Limited
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| Tel: |
18024082417 |
| Email: |
market@ubiochem.com |
| Products Intro: |
Product Name:TMP780
CAS:1422053-03-9
Purity:5mg;10mg;50mg;100mg;250mg;500mg;1g Package:5mg;10mg;50mg;100mg;250mg;500mg;1g
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| Product Name: | TMP780 | | Synonyms: | TMP780;TMP780,TMP-780;5-Benzofuranacetamide, 2-[(R)-(3,5-dimethyl-4-isoxazolyl)hydroxymethyl]-N-[(S)-(2,4-dimethylphenyl)phenylmethyl]- | | CAS: | 1422053-03-9 | | MF: | C31H30N2O4 | | MW: | 494.58 | | EINECS: | | | Product Categories: | | | Mol File: | 1422053-03-9.mol |  |
| | TMP780 Chemical Properties |
| Boiling point | 752.7±60.0 °C(Predicted) | | density | 1?+-.0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 220 mg/mL (444.82 mM; Need ultrasonic) | | pka | 12.47±0.20(Predicted) |
| | TMP780 Usage And Synthesis |
| Biological Activity | TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1]. | | References | [1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75. |
| | TMP780 Preparation Products And Raw materials |
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