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Postion:Product Catalog >Geissoschizine methyl ether
Geissoschizine methyl ether
  • Geissoschizine methyl ether
  • Geissoschizine methyl ether
  • Geissoschizine methyl ether
  • Geissoschizine methyl ether
  • Geissoschizine methyl ether

Geissoschizine methyl ether

Price $9.8
Package 1KG
Min. Order: 1KG
Supply Ability: 20 tons
Update Time: 2020-01-10

Product Details

Product Name: Geissoschizine methyl ether CAS No.: 60314-89-8
Min. Order: 1KG Purity: ≥98%
Supply Ability: 20 tons Release date: 2020/01/10
Storage:: Keep away from heat, sparks and flames Package:: Bottle / Drum / Bag
Delivery Time:: Prompt Port:: Shanghai, Tianjin or Qingdao
Transportation:: By sea, express, air,railway Product No. :: Jessie

Jessie 0569

Contact : jessie@coreychem.com

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[Product Specification]

Names

Name
Geissoschizine methyl ether
Synonym
More Synonyms

 Geissoschizine methyl ether Biological Activity

Description
Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist[1][2].
Related Catalog
Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target

5-HT1A[2]

References

[1]. Matsumoto T, et al. In vitro identification of human cytochrome P450 isoforms involved in the metabolism of Geissoschizine methyl ether, an active component of the traditional Japanese medicine Yokukansan. Xenobiotica. 2016;46(4):325-34.

[2]. Nishi A, et al. Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan. Neuroscience. 2012 Apr 5;207:124-36.

 Chemical & Physical Properties

Density
1.2±0.1 g/cm3
Molecular Formula
C22H26N2O3
Molecular Weight
366.45300
Exact Mass
366.19400
PSA
54.56000
LogP
3.67450
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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