Aspirin NEW

Factory Provide High Purity CAS 50-78-2 Bulk Aspirin Powder

Introduction

Product Name :Aspirin

Othe name :O-ACETOXYBENZOIC ACID;2-Acetoxybenzoesre,Acetylsalicylic acid

CAS No. 50-78-2

EINECS No. 200-064-1

Molecular Formula: C9H8O4

MW:180.16

Assay: 99%
Appearance: White powder
Melting Point :134-136 °C (lit.)

Boiling Point :272.96°C (rough estimate)

Density :1.35 g/cm3(Predicted)

Storage :Keep in a cool, dry, dark location

Aspirin, also known as acetylsalicylic acid, belongs to non-steroidal anti-inflammatory drugs and was first used for anti-inflammatory and analgesia.  Aspirin was later discovered to prevent platelets from clumping together to achieve the antithrombotic effect.  As research on aspirin continues, many new uses have been discovered, such as reducing deaths from heart attacks and strokes, and reducing the risk of colorectal cancer.

Function
Acetylsalicylic acid (aspirin) is a traditional antipyretic analgesic and has the effect of anti-platelet aggregation.  Acetylsalicylic acid (aspirin) has antithrombotic properties in vivo and can reduce the formation of obstructive thrombosis in peripheral arteries.  Inhibit platelet release response and endogenous ADP, 5-HT release.  Therefore, inhibition of the second phase of platelet aggregation without inhibition of the first phase of aggregation.  Acetylsalicylic acid (aspirin) works by acetylation of cyclooxygenase in platelets, thereby inhibiting intra-ring peroxide formation and reducing TXChemicalbookA2 production.  At the same time, it can also acetylate platelet membrane protein and inhibit platelet membrane enzyme, which also helps to inhibit platelet function.  The inhibition of cyclooxygenase affects the synthesis of PGI2 in vascular wall.  TXA2 synthesis of platelet enzymes can also be inhibited, such as large doses of TXA2 and PGI2 generation are affected.  Suitable for ischemic heart disease, coronary artery angioplasty (PTCA), coronary artery bypass surgery, can prevent transient cerebral ischemia, stroke, myocardial infarction, reduce the incidence of arrhythmia.

Application
It can inhibit platelet aggregation and prevent thrombosis. It is clinically used to prevent temporary cerebral ischemia attack, myocardial infarction, arterial thrombosis and atherosclerosis.  Additional, still can treat biliary ascariasis disease.