Repaglinide NEW
| Price | $8 | $3 | $1 |
| Package | 1KG | 25KG | 100KG |
| Min. Order: | 1KG |
| Supply Ability: | g-kg-tons, free sample is available |
| Update Time: | 2024-03-29 |
Product Details
| Product Name: Repaglinide | CAS No.: 135062-02-1 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2024/03/29 |
| Lead time: In stock, ready for shipment | IIn stock, r: bag/bottle/drum/IBC |
| bag/bottle: By express, by air, by sea | Origin: Manufacturer, advantage product |
| COA, MS: Available, contact us for details | NAME: Sun |
1. Materials information
| Name | Repaglinide |
|---|---|
| Synonym | More Synonyms |
| Description | Repaglinide(AG-EE 623ZW) is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes. IC50 value:Target: Repaglinide is very rapidly absorbed (tmax less than 1 hour) with a t1/2 of less than one hour. Furthermore, repaglinide is inactivated in the liver and more than 90 % excreted via the bile. Repaglinide (1 mg/kg p.o.) was effective (P < 0.001) as an insulin-releasing agent in a rat model (low-dose streptozotocin) of type 2 diabetes. |
|---|---|
| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease |
| References | [1]. Marbury T, Huang WC, Strange P, Lebovitz H et al. Repaglinide versus glyburide: a one-year comparison trial. Diabetes Research and Clinical Practice .1999, 43(3):155-166. [2]. David R. Owens . Repaglinide-prandial glucose regulator: a new class of oral antidiabetic drugs . Diabetic Medicine 1998,15 : S28-S36. [3]. J Fuhlendorff, P Rorsman, H Kofod. Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes. Diabetes. 1998. 47 (3): 345-351 . [4]. R Moses, R Slobodniuk, S Boyages. Effect of repaglinide addition to metformin monotherapy on glycemic control in patients with type 2 diabetes. Diabetes Care . 22 (1 ) : 119-124 . [5]. Julio Rosenstock, MD, David R. Hassman, DO, Robert D. Madder, DO. Diabetes Care June 2004 vol. 27 no. 6 1265-1270 [6]. Shiling Hu1, Shuya Wang1, Barbara Fanelli1. Pancreatic β-Cell KATP Channel Activity and Membrane-Binding Studies with Nateglinide: A Comparison with Sulfonylureas and Repaglinide . JPET , 2000,293 (2 ): 444-452 . |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 672.9±55.0 °C at 760 mmHg |
| Melting Point | 129-130.2 °C |
| Molecular Formula | C27H36N2O4 |
| Molecular Weight | 452.586 |
| Flash Point | 360.8±31.5 °C |
| Exact Mass | 452.267517 |
| PSA | 78.87000 |
| LogP | 4.69 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.568 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: 34 mg/mL |
Repaglinide MSDS(Chinese) |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | 000000033825 |
| HS Code | 2933399090 |
 Repaglinide eth... 147770-06-7 ~92%  Repaglinide 135062-02-1 |
| Literature: Grell, Wolfgang; Hurnaus, Rudolf Journal of Medicinal Chemistry, 1998 , vol. 41, # 26 p. 5219 - 5246 |
 N/A 147769-96-8 ~% Repaglinide 135062-02-1 |
| Literature: Chimia, , vol. 60, # 9 p. 593 - 597 |
 Piperidine 110-89-4 ~% Repaglinide 135062-02-1 |
| Literature: Journal of Medicinal Chemistry, , vol. 41, # 26 p. 5219 - 5246 |
| Precursor 5 | Previous 1/2 Next |
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| DownStream 0 | |
CAS#:72752-52-4
CAS#:873-32-5| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: Sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 86 13526505137
Company Profile Introduction
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- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro