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ChemicalBook >>Indapamide>>N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline(26807-65-8)

N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline(26807-65-8)

N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline(26807-65-8)
Product IdentificationBack to Contents
【Product Name】

N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
【Synonyms】

3-(Aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide
Lonzol
N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
Natrilix
Tandix
Veroxil
【CAS】

26807-65-8
【Formula】

C16H16ClN3O3S
【Molecular Weight】

365.84
【EINECS】

248-012-7
【RTECS】

CV2451200
【RTECS Class】

Drug; Reproductive Effector
【Merck】

12,4969
【Beilstein/Gmelin】

1604026
【Beilstein Reference】

5-20-06-00348
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Insoluble
【pKa/pKb】

9.35 (pKa)
【Usage】

A thiazide-like diuretic used, either alone or in combination with other drugs, to treat high blood pressure and to prevent salt and fluid retention associated with heart failure.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
【Exposure Effects】

Avoid contact and inhalation. Target organ(s): Kidneys.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Decomposition】

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.
Hazards IdentificationBack to Contents
【Hazards】

Emits toxic fumes under fire conditions.
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