ChemicalBook >>Broxuridine>>5-Bromo-2'-deoxyuridine(59-14-3)

5-Bromo-2'-deoxyuridine(59-14-3)

5-Bromo-2'-deoxyuridine(59-14-3)
Product IdentificationBack to Contents
【Product Name】

5-Bromo-2'-deoxyuridine
【Synonyms】

2'-Deoxy-5-bromouridine
5-BDU
5-Bromo-2-deoxyuridine
5-Bromodeoxyuridine
5-Bromodesoxyuridine
Bromodeoxyuridine
【CAS】

59-14-3
【Formula】

C9H11BrN2O5
【Molecular Weight】

307.10000000000002
【EINECS】

200-415-9
【RTECS】

YU7350000
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector
【Merck】

12,10433
【Beilstein/Gmelin】

30395
【Beilstein Reference】

4-24-00-01234
Physical and Chemical PropertiesBack to Contents
【Appearance】

White crystalline powder.
【Solubility in water】

Slightly soluble
【Melting Point】

192 - 193
【pKa/pKb】

7.85 (pKa)
【Usage】

Makes cancer cells more sensitive to radiation and is also used as a diagnostic agent to determine how fast cancer cells grow.
【Vapor Density】

10.6
First Aid MeasuresBack to Contents
【Ingestion】

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration.
【Skin】

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Deep freeze (below -20 C).
【Handling】

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Low hazard for usual industrial handling.
【Inhalation】

May cause respiratory tract irritation. Low hazard for usual industrial handling.
【Skin】

May cause skin irritation. May cause erythema, and edema with crusting and scaling.
【Eyes】

May cause eye irritation.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing agents.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide, nitrogen.
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