ChemicalBook >>Verapamil>>(2R)-2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile(52-53-9)

(2R)-2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile(52-53-9)

(2R)-2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile(52-53-9)
Product IdentificationBack to Contents
【Product Name】

(2R)-2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile
【Synonyms】

2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile
Dilacoran
【CAS】

52-53-9
【Formula】

C27H38N2O4
【Molecular Weight】

454.61
【EINECS】

200-145-1
【RTECS】

YV8300000
【RTECS Class】

Drug; Reproductive Effector; Human Data
【Merck】

12,10083
【Beilstein/Gmelin】

2825000
Physical and Chemical PropertiesBack to Contents
【Appearance】

Viscous, pale yellow oil.
【Solubility in water】

practically insoluble
【Boiling Point】

232 - 235 (0.01 torr)
【pKa/pKb】

8.6(at 25℃) (pKa)
【Usage】

Calcium channel blocker.
【Refractive Index】

1.5448 (25 C)
First Aid MeasuresBack to Contents
【Ingestion】

Flush mouth with water. See medical assistance.
【Inhalation】

Remove to fresh air.
【Skin】

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush with water and seek medical assistance.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry location in a tightly closed container.
【Handling】

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards IdentificationBack to Contents
【Inhalation】

Respiratory effects are uncommon but noncardiogenic pulmonary edema, may occur following significant overdose.
【Skin】

Causes irritation. Flushing is common with nifedipine.
【Eyes】

Causes irritation.
【Ingestion】

Nausea and vomiting occur frequently. Ileus can also occur. Concretions from sustained-release dosage forms have been found at autopsy. Bowel infarction has also been reported.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Latex gloves, chemical safety goggles and disposable protective clothing.
【Respirators】

A NIOSH approved respirator should be available.
【Exposure Effects】

CNS depression, secondary to hemodynamic instability occurs following significant overdose. Effects may include drowsiness, confusion, and coma. Cerebral infarction has been reported.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear self contained breathing apparatus and protective clothing. Use water spray, carbon dioxide, dry chemical or foam to extinguish fire.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

While wearing recommended personal protective equipment, absorb liquid with paper and place in a container for disposal.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Combustion Products】

May emit toxic fumes.
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