| Product Identification | Back to Contents | 【Product Name】
(+)-2-(6-Methoxy-2-naphthyl)-propionic acid | 【Synonyms】
(1)-2-(6-Methoxy-2-naphthyl)propionic acid
2-(6-Methoxynaphthalen-2-yl)propanoic acid
Cg 3117
Diocodal
Dysmenalgit n
Naphthaleneacetic acid, 6-methoxy-.alpha.-methyl-, (S)- | 【CAS】
22204-53-1 | 【Formula】
C14H14O3 | 【Molecular Weight】
230.26 | 【EINECS】
244-838-7 | 【RTECS】
UF5275000 | 【RTECS Class】
Drug; Mutagen; Reproductive Effector; Human Data | 【Merck】
12,6504 | 【Beilstein/Gmelin】
3591067 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Crystals from acetone-hexane. Practically odorless. | 【Solubility in water】
Insoluble | 【Melting Point】
156 | 【Boiling Point】
404 | 【Vapor Pressure】
3E-7 (25 C) | 【pKa/pKb】
4.15 (pKa) | 【Partition Coefficient】
3.24 | 【Heat Of Vaporization】
69.1 kJ/mol | 【Usage】
Anti-inflammatory drug. |
| First Aid Measures | Back to Contents | 【Ingestion】
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Inhalation】
Apnea has developed secondary to seizures following overdose. - Pulmonary infiltrates with eosinophilia has occurred with chronic therapeutic use. Bronchoconstriction and asthma has been reported after initial dosing. | 【Skin】
Photosensitivity and pseudoporphyria has been described in chronic therapeutic use. Necrotizing vasculitis has been reported with short term use. | 【EC Risk Phrase】
R 22 36/37/38 | 【EC Safety Phrase】
S 26 36/37/39 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | 【Exposure Effects】
CNS depression and seizures (focal and generalized) have occurred following overdose. A. Dizziness and dystonic movement disorders have also been reported. With therapeutic use - aseptic meningitis has been associated with naproxen. Naproxen is pregnancy category B. <br> 1. Risk Factor D if used in 3rd trimester or near delivery. <br>Because of known effects of the fetus (closure of ductus arteriosus), it should be avoided during late pregnancy. <br>Naproxen has been found in the milk of lactating women; however, The American Academy of Pediatrics considers naproxen to be compatible with breast feeding (Briggs et al, 1998). |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
155 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
|
| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
|