| Product Identification | Back to Contents | 【Product Name】
Leurocristine sulfate salt | 【Synonyms】
Kyocristine
Leurocristine sulfate (1:1)
Oncovin
Vincaleukoblastine, 22-oxo-, sulfate (1:1)
Vincaleukoblastine, 22-oxo-, sulfate (1:1) (salt) | 【CAS】
2068-78-2 | 【Formula】
C46H58N4O14S | 【Molecular Weight】
923.14 | 【EINECS】
218-190-0 | 【RTECS】
OH6340000 | 【RTECS Class】
Tumorigen; Drug; Mutagen; Reproductive Effector | 【Beilstein/Gmelin】
3924631 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
An anticancer drug. Odorless. | 【Solubility in water】
Soluble | 【Melting Point】
277.2 | 【Usage】
Treatment of acute leukemia, hodgkin's disease, soft-tissue sarcoma, bony-tissue sarcoma, sarcomas of specialized structures, breast cancer, small cell cancer of the lung, cancer of the uterine cervix, malignant melanoma, colorectal cancer, non-hodgkin's lymphoma and wilms' tumor. |
| First Aid Measures | Back to Contents | 【Ingestion】
DO NOT INDUCE VOMITING. Strychnine is an exceptionally toxic poison but inducing vomiting may cause a seizure. IMMEDIATELY call a hospital or poison control center and locate activated charcoal, egg whites, or milk in case the medical advisor recommends administering one of them. If advice from a physician is not readily available and the victim is conscious and not convulsing, give the victim a glass of activated charcoal slurry in water or, if this is not available, a glass of milk, or beaten egg whites and IMMEDIATELY transport victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. | 【Inhalation】
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used. | 【Skin】
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. | 【Eyes】
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Ingestion】
See Inhalation. | 【Inhalation】
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed. | 【Skin】
Contact with molten substance may cause severe burns to skin and eyes. See Inhalation. | 【Eyes】
See Inhalation. | 【Hazards】
Contact with metals may evolve flammable hydrogen gas. | 【UN (DOT)】
2811 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Wear appropriate protective gloves, clothing and goggles. | 【Respirators】
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. | 【Fire Potential】
This material is probably combustible. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Stability and Reactivity | Back to Contents | 【Stability】
No data. | 【Incompatibilities】
Sensitive to hydrolysis, oxidation and heat Incompatible with strong oxidizing agents. | 【Combustion Products】
Fire may produce irritating, corrosive and/or toxic gases. |
|
| Company Name: |
Kono Chem Co.,Ltd |
| Tel: |
029-86107037-8009 13279399072 |
| Fax: |
13279399072 |
| WebSite: |
http://www.konochemical.com |
| Company Name: |
Wuhan Wsem Biological Co., Ltd. |
| Tel: |
027-83778876 13667159345 |
| Fax: |
027-83778876 |
| WebSite: |
https://www.chemicalbook.com/ShowSupplierProductsList19944/0.htm |
| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
|