产品属性:
产品名称 | 规格 | CAS号 | 型号 |
5-hydroxy Tryptophol | 25mg 100mg | 154-02-9 | EY-Y0163621 |
Cas No.154-02-9
别名 NSC 84416
化学名 5-hydroxy-1H-indole-3-ethanol
分子式 C10H11NO2
分子量 177.2
溶解度 ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
5-hydroxy Tryptophol is a metabolite of tryptophan.
Tryptophan (encoded by the codon UGG) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan has an α-amino group, an α-carboxylic acid group, and a side chain indole, demonstrating it as a non-polar, aromatic amino acid. Tryptophan is critical in humans, but the body cannot synthesize it and therefore tryptophan must be obtained from the diet. Tryptophan is also found to be a precursor to the neurotransmitters serotonin and melatonin.
In vitro: In previous studies, 5-hydroxy tryptophol was identified as a metabolite of tryptophan that was formed by the alcohol dehydrogenase-catalyzed reduction of the serotonin intermediate, 5-hydroxyindoleacetaldehyde. Moreover, depending on the tissue NAD/NADH ratio, the acetaldehyde intermediate could also be oxidized by aldehyde dehydrogenase to form 5-hydroxyindoleacetic acid. Therefore, the ratio of 5-hydroxy tryptophol to 5-hydroxyindoleacetic acid could be used as a biomarker for recent alcohol consumption [1,2].
In vivo: Up to now, there is no animal in vivo data reported.
Clinical trial: So far, no clinical study has been conducted.
关键字: 154-02-9;C10H11NO2;5-hydroxy Tryptophol;
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