产品属性:
产品名称 | 规格 | CAS号 | 型号 |
Beauvericin | 1mg 5mg 10mg | 26048-05-5 | EY-Y0163919 |
Cas No.26048-05-5
别名 N/A
化学名 (3S,9S,15S)-3,9,15-tribenzyl-6,12,18-triisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexaone
分子式 C45H57N3O9
分子量 783.95
溶解度 DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants.[1] Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 μM.[2] In mammalian cells, beauvericin induces apoptosis with an IC50 value of 4.5 μM.[1],[3]
Reference:
[1]. Logrieco, A., Moretti, A., Castella, G., et al. Beauvericin production by Fusarium species. Applied and Environmental Microbiology 64(8), 3084-3088 (1998).
[2]. Calo, L., Fornelli, F., Nenna, S., et al. Beauvericin cytotoxicity to the invertebrate cell line SF-9. J.Appl.Genet. 44(4), 515-520 (2003).
[3]. Tonshin, A.A., Teplova, V.V., Andersson, M.A., et al. The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis. Toxicology 276, 49-57 (2010).
关键字: 26048-05-5;C45H57N3O9;Beauvericin;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业,公司自成立以来,秉承""全心全意服务于科研工作者""的企业理念,立足生物科技领域,运用生物技术和科研试剂,发展现代生物科技,为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品,服务生物科技领域的科学研究人员。
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