Rabbit Anti-G6PC Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:G6PC
IR:Immunogen Range:81-180/357
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2538
Swiss Prot:P35575
Source:KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha:81-180/357
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Flow-Cyt(0.2ug/test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
Sheep
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： G6PC;glucose-6-phosphatas;catalytic subunit;GSD1;AW107337;G-6-Pase;G6Pase;G6Pase-alpha;
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