Rabbit Anti-FAM126A Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FAM126A
IR:Immunogen Range:1-100/521
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:84668
Swiss Prot:Q9BYI3
Source:KLH conjugated synthetic peptide derived from human FAM126A:1-100/521
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Hyccin is a 521 amino acid cytoplasmic protein that is widely expressed with highest levels found in heart, brain, placenta, spleen and testis. Belonging to the FAM126 family, hyccin may play a role in the ∫-catenin/Lef signaling pathway. Hyccin is likely involved in the process of myelination of the central and peripheral nervous system. Defects in the gene encoding hyccin are the cause of leukodystrophy hypomyelinating type 5 (HLD5), which is characterized by congenital cataract, progressive neurologic impairment and diffuse myelin deficiency. Individuals affected by HLD5 experience progressive pyramidal and cerebellar dysfunction along with muscle weakness in the lower limbs. Hyccin exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 7.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： FAM126A;Hyccin;Down regulated by Ct;Down regulated by CT;FAM126A;DRCTNNB1A;HLD5;HYCCI_HUMAN ;
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