4-[(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHALENYL)CARBOXAMIDO]BENZOIC ACID
![4-[(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHALENYL)CARBOXAMIDO]BENZOIC ACID price.](/CAS/GIF/102121-60-8.gif)
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- $32 - $1949.9
- Product name: 4-[(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHALENYL)CARBOXAMIDO]BENZOIC ACID
- CAS: 102121-60-8
- MF: C22H25NO3
- MW: 351.44
- EINECS:
- MDL Number:MFCD00673916
- Synonyms:4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]benzoic acid;NSC 608001;4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid;benzoicacid,4-((5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbony ;cd336 ;l)amino- ;ro40-6055 ;AM 580
41 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10
- 1MG
- 10mg
- 50
- 25mg
- 50MG
- 100mg
- 250mg
- 10mM(in 1mL DMSO)
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product number3437AH
- Product description4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]benzoicacid
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65155
- Product descriptionAM 580
- Packaging10mg
- Price$131.65
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008429
- Product descriptionAM 580 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008429
- Product descriptionAM 580 95.00%
- Packaging10MG
- Price$697.34
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008429
- Product descriptionAM 580 95.00%
- Packaging50MG
- Price$1170.31
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4654
- Product descriptionAM 580
- Packaging10mM(in 1mL DMSO)
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4654
- Product descriptionAM 580
- Packaging10mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4654
- Product descriptionAM 580
- Packaging50mg
- Price$361
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS467988
- Product descriptionAM 580 ≥98%
- Packaging100mg
- Price$194
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180917
- Product descriptionAM 580 >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180917
- Product descriptionAM 580 >98%
- Packaging250mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180917
- Product descriptionAM 580 >98%
- Packaging1000mg
- Price$1949.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA137469
- Product descriptionAM 580
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA137469
- Product descriptionAM 580
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15261
- Product descriptionAM 580 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15261
- Product descriptionAM 580 ≥98%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3437AH | 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]benzoicacid | 5mg | $150 | 2021-12-16 | Buy |
| Alfa Aesar | J65155 | AM 580 | 10mg | $131.65 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0008429 | AM 580 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008429 | AM 580 95.00% | 10MG | $697.34 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008429 | AM 580 95.00% | 50MG | $1170.31 | 2021-12-16 | Buy |
| ApexBio Technology | B4654 | AM 580 | 10mM(in 1mL DMSO) | $75 | 2021-12-16 | Buy |
| ApexBio Technology | B4654 | AM 580 | 10mg | $100 | 2021-12-16 | Buy |
| ApexBio Technology | B4654 | AM 580 | 50mg | $361 | 2021-12-16 | Buy |
| Arctom | AS467988 | AM 580 ≥98% | 100mg | $194 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180917 | AM 580 >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180917 | AM 580 >98% | 250mg | $986 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180917 | AM 580 >98% | 1000mg | $1949.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA137469 | AM 580 | 10mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA137469 | AM 580 | 50mg | $437.5 | 2021-12-16 | Buy |
| Cayman Chemical | 15261 | AM 580 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15261 | AM 580 ≥98% | 5mg | $93 | 2024-03-01 | Buy |
Properties
Melting point :265-267℃
Boiling point :485.24°C (rough estimate)
Density :1.154
refractive index :1.5614 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (20mg/ml) or ethanol (10mg/ml).
form :White to off-white solid.
pka :4.28±0.10(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :485.24°C (rough estimate)
Density :1.154
refractive index :1.5614 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (20mg/ml) or ethanol (10mg/ml).
form :White to off-white solid.
pka :4.28±0.10(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
AM580 is a retinoic acid receptor agonist that is selective for RARα (Kd = 8 nM; AC50 = 0.36 nM) compared to RARβ (Kd = 131 nM; AC50 = 24.6 nM) and RARγ (Kd = 450 nM; AC50 = 27.9 nM). It demonstrates greater specific binding to RARα compared to retinoic acid , which exhibits little selectivity across RARα, β, or γ. AM580 has been used in combination with the GSK3β inhibitor CHIR99021 to efficiently induce differentiation of human induced pluripotent stem cells into immediate mesoderm. It can also inhibit the proliferation of various tumor cells, inhibiting survival signaling pathways and inducing apoptosis.Related product price
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