5,15-DIPHENYL-21H,23H-PORPHINE
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- $32 - $1645.88
- Product name: 5,15-DIPHENYL-21H,23H-PORPHINE
- CAS: 22112-89-6
- MF: C32H22N4
- MW: 462.54
- EINECS:
- MDL Number:MFCD08276335
- Synonyms:5,15-DIPHENYL-21H,23H-PORPHINE;5,15-DIPHENYLPORPHINE;5, 15-BIS-(PHENYL)PORPHYRINS;5,15-Diphenylporphyrin;5,15-Bis-(phenyl)-21H,23H-porphyrins;5,15-DPP;Stat3 Inhibitor VIII, 5,15-DPP;STAT3 Inhibitor VIII, 5,15-DPP - CAS 22112-89-6 - Calbiochem
19 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chem-Impex
- Crysdot
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1209AB
- Product description5,15-Diphenyl-21H,23H-porphine
- Packaging1g
- Price$1362
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number22112896
- Product description5,15-Diphenyl-21H,23H-porphine
- Packaging250mg
- Price$252.28
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number22112896
- Product description5,15-Diphenyl-21H,23H-porphine
- Packaging1g
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0005851
- Product description5,15-DIPHENYL-21H,23H-PORPHINE 95.00%
- Packaging1G
- Price$1645.88
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3975
- Product description5, 15-DPP
- Packaging25mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3975
- Product description5, 15-DPP
- Packaging50mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3975
- Product description5, 15-DPP
- Packaging100mg
- Price$269
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16090
- Product description5, 15-DPP ≥95%
- Packaging10mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16090
- Product description5, 15-DPP ≥95%
- Packaging25mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16090
- Product description5, 15-DPP ≥95%
- Packaging50mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16090
- Product description5, 15-DPP ≥95%
- Packaging100mg
- Price$236
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number38690
- Product description5,15-Diphenylporphyrin,≥90%(HPLC) ≥90%(HPLC)
- Packaging100MG
- Price$337.79
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11163820
- Product description5,15-Diphenyl-21H,23H-porphine 95+%
- Packaging1g
- Price$595
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number058084
- Product description5,15-Diphenyl-21H,23H-porphine 95%
- Packaging1g
- Price$972
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberD4071
- Product description5, 15-DPP
- Packaging10mg
- Price$87.5
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number573109
- Product descriptionSTAT3 Inhibitor VIII, 5,15-DPP
- Packaging25mg
- Price$140
- Updated2023-01-07
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1209AB | 5,15-Diphenyl-21H,23H-porphine | 1g | $1362 | 2021-12-16 | Buy |
| Alichem | 22112896 | 5,15-Diphenyl-21H,23H-porphine | 250mg | $252.28 | 2021-12-16 | Buy |
| Alichem | 22112896 | 5,15-Diphenyl-21H,23H-porphine | 1g | $480 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0005851 | 5,15-DIPHENYL-21H,23H-PORPHINE 95.00% | 1G | $1645.88 | 2021-12-16 | Buy |
| ApexBio Technology | C3975 | 5, 15-DPP | 25mg | $123 | 2021-12-16 | Buy |
| ApexBio Technology | C3975 | 5, 15-DPP | 50mg | $208 | 2021-12-16 | Buy |
| ApexBio Technology | C3975 | 5, 15-DPP | 100mg | $269 | 2021-12-16 | Buy |
| Cayman Chemical | 16090 | 5, 15-DPP ≥95% | 10mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 16090 | 5, 15-DPP ≥95% | 25mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 16090 | 5, 15-DPP ≥95% | 50mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 16090 | 5, 15-DPP ≥95% | 100mg | $236 | 2024-03-01 | Buy |
| Chem-Impex | 38690 | 5,15-Diphenylporphyrin,≥90%(HPLC) ≥90%(HPLC) | 100MG | $337.79 | 2021-12-16 | Buy |
| Crysdot | CD11163820 | 5,15-Diphenyl-21H,23H-porphine 95+% | 1g | $595 | 2021-12-16 | Buy |
| Matrix Scientific | 058084 | 5,15-Diphenyl-21H,23H-porphine 95% | 1g | $972 | 2021-12-16 | Buy |
| Sigma-Aldrich | D4071 | 5, 15-DPP | 10mg | $87.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 573109 | STAT3 Inhibitor VIII, 5,15-DPP | 25mg | $140 | 2023-01-07 | Buy |
Properties
Melting point :>200℃
Boiling point :912.3±65.0 °C(Predicted)
Density :1.285±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :≤2mg/ml in dimethyl formamide
form :Deep blue to deep purple solid
color :Red to Dark blue to Black
Boiling point :912.3±65.0 °C(Predicted)
Density :1.285±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :≤2mg/ml in dimethyl formamide
form :Deep blue to deep purple solid
color :Red to Dark blue to Black
Safety Information
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Description
Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer. 5,15-DPP is a cell-permeable porphyrin derivative that selectively binds STAT3 (Kd = 880 nM). This inhibits STAT3 dimerization via Src homology 2 (Sh2) domains (IC50 = 280 nM), preventing nuclear translocation and DNA binding. 5,15-DPP poorly inhibits STAT1 (IC50 = 10 μM) and does not affect Grb2. It reduces IL-6-dependent STAT3 activation and consequent c-myc expression in MDA-MB-468 cells and blocks TRAIL-induced migration and invasion in A549 cells. Furthermore, inhibition of JAK/STAT signaling in satellite cells via 5,15-DPP and the JAK2 inhibitor AG-490 has been used to stimulate muscle regeneration in a model of aging skeletal muscle deterioration.More related product prices
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