AZD-8055
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- $26 - $2395.3
- Product name: AZD-8055
- CAS: 1009298-09-2
- MF: C25H31N5O4
- MW: 465.54
- EINECS:-0
- MDL Number:MFCD16660191
- Synonyms:AZD 8055 [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol;AZD8055, >=98%;Propanoic acid, 2,2-dimethyl-, [5-(2,4-dichloropyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl]methyl ester;(5-{2,4-dichloropyrido[2,3-d]pyriMidin-7-yl}-2-Methoxyphenyl)Methyl 2,2-diMethylpropanoate;[5-[2,4-Bis((3S)-3-MethylMorpholin-4-yl)pyrido[;5-[2,4-Bis[(3S)-3-Methyl-4-Morpholinyl]pyrido[2,3-d]pyriMidin-7-yl]-2-MethoxybenzeneMethanol;CCG 168;AZD8055,AZD-8055
37 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 2x25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1166-M050
- Product descriptionAZD-8055 ≥95%
- Packaging50mg
- Price$346
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7420
- Product descriptionAZD8055
- Packaging50mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA224432
- Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
- Packaging5mg
- Price$26
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA224432
- Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
- Packaging10mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA224432
- Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
- Packaging50mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA224432
- Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
- Packaging100mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA224432
- Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
- Packaging250mg
- Price$371
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA224432
- Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
- Packaging1g
- Price$927
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000924
- Product descriptionAZD-8055 95.00%
- Packaging10MG
- Price$779.63
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000924
- Product descriptionAZD-8055 95.00%
- Packaging100MG
- Price$2194.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8214
- Product descriptionAZD8055
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60002
- Product descriptionAZD8055 ≥98%
- Packaging20mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1561
- Product descriptionAZD8055 99%
- Packaging2x25mg
- Price$396
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546257
- Product descriptionAZD8055 >98%
- Packaging10mg
- Price$146.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546257
- Product descriptionAZD8055 >98%
- Packaging50mg
- Price$314.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154690
- Product descriptionAZD-8055 >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1166-M050 | AZD-8055 ≥95% | 50mg | $346 | 2021-12-16 | Buy |
| AK Scientific | X7420 | AZD8055 | 50mg | $132 | 2021-12-16 | Buy |
| Ambeed | A224432 | (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% | 5mg | $26 | 2021-12-16 | Buy |
| Ambeed | A224432 | (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% | 10mg | $45 | 2021-12-16 | Buy |
| Ambeed | A224432 | (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% | 50mg | $98 | 2021-12-16 | Buy |
| Ambeed | A224432 | (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% | 100mg | $188 | 2021-12-16 | Buy |
| Ambeed | A224432 | (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% | 250mg | $371 | 2021-12-16 | Buy |
| Ambeed | A224432 | (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% | 1g | $927 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000924 | AZD-8055 95.00% | 10MG | $779.63 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000924 | AZD-8055 95.00% | 100MG | $2194.5 | 2021-12-16 | Buy |
| ApexBio Technology | A8214 | AZD8055 | 10mg | $50 | 2021-12-16 | Buy |
| Arctom | CFN60002 | AZD8055 ≥98% | 20mg | $198 | 2021-12-16 | Buy |
| Axon Medchem | Axon1561 | AZD8055 99% | 2x25mg | $396 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546257 | AZD8055 >98% | 10mg | $146.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546257 | AZD8055 >98% | 50mg | $314.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154690 | AZD-8055 >98% | 100mg | $615.4 | 2021-12-16 | Buy |
Properties
Melting point :204 - 207°C
Boiling point :694.3±65.0 °C(Predicted)
Density :1.248
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml)
form :Yellow powder.
pka :14.20±0.10(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Boiling point :694.3±65.0 °C(Predicted)
Density :1.248
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml)
form :Yellow powder.
pka :14.20±0.10(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
AZD 8055 is a potent, selective ATP-competitive inhibitor of mTOR, exhibiting an IC50 value of 0.8 nM. It is ~1,000-fold selective for mTOR over all PI3K isoforms and exhibits no activity against a panel of 260 kinases at concentrations up to 10 μM. AZD 8055 inhibits proliferation of A549 and H838 cells with IC50 values of 53 and 20 nM, respectively. It inhibits growth of a variety of human tumor xenografts by at least 65% in mice at daily oral doses of 20 mg/kg.Related product price
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