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ChemicalBook >> CAS DataBase List >> Epirubicin hydrochloride

Epirubicin hydrochloride

Epirubicin hydrochloride price.
  • $12 - $2000
  • Product name: Epirubicin hydrochloride
  • CAS: 56390-09-1
  • MF: C27H30ClNO11
  • MW: 579.9802
  • EINECS:260-145-2
  • MDL Number:MFCD00274554
  • Synonyms:4’-epi-adriamycinhydrochloride ;5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-alpha-l-arabino-hexopyranosy ;8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-l)oxy)-hyd ;EPIRUBICIN HYDROCHLORIDE EP STANDARD;EpirubicinHc,LEp5,;Adrial;(8S,10S)-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione, hydrochloride (1:1);5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, hydrochloride (1:1), (8S,10S)-
62 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 10mM(in 1mL DMSO)
  • 1mg
  • e0550000
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberJ54141
  • Product descriptionEpirubicinHCl
  • Packaging25mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ54141
  • Product descriptionEpirubicinHCl
  • Packaging50mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ54141
  • Product descriptionEpirubicinHCl
  • Packaging100mg
  • Price$379
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60411
  • Product descriptionEpirubicin hydrochloride
  • Packaging10mg
  • Price$244
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60411
  • Product descriptionEpirubicin hydrochloride
  • Packaging100mg
  • Price$944
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA263227
  • Product description(8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
  • Packaging1mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA263227
  • Product description(8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
  • Packaging5mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA263227
  • Product description(8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA263227
  • Product description(8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
  • Packaging25mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA263227
  • Product description(8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
  • Packaging100mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002568
  • Product descriptionEPIRUBICIN HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002568
  • Product descriptionEPIRUBICIN HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$744.86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002568
  • Product descriptionEPIRUBICIN HYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$890.39
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2451
  • Product descriptionEpirubicinHCl
  • Packaging5mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2451
  • Product descriptionEpirubicinHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2451
  • Product descriptionEpirubicinHCl
  • Packaging25mg
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J54141 EpirubicinHCl 25mg $139 2021-12-16 Buy
AK Scientific J54141 EpirubicinHCl 50mg $228 2021-12-16 Buy
AK Scientific J54141 EpirubicinHCl 100mg $379 2021-12-16 Buy
Alfa Aesar J60411 Epirubicin hydrochloride 10mg $244 2024-03-01 Buy
Alfa Aesar J60411 Epirubicin hydrochloride 100mg $944 2024-03-01 Buy
Ambeed A263227 (8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+% 1mg $12 2021-12-16 Buy
Ambeed A263227 (8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+% 5mg $27 2021-12-16 Buy
Ambeed A263227 (8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+% 10mg $39 2021-12-16 Buy
Ambeed A263227 (8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+% 25mg $67 2021-12-16 Buy
Ambeed A263227 (8S,10S)-10-(((2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+% 100mg $220 2021-12-16 Buy
American Custom Chemicals Corporation API0002568 EPIRUBICIN HYDROCHLORIDE 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation API0002568 EPIRUBICIN HYDROCHLORIDE 95.00% 10MG $744.86 2021-12-16 Buy
American Custom Chemicals Corporation API0002568 EPIRUBICIN HYDROCHLORIDE 95.00% 25MG $890.39 2021-12-16 Buy
ApexBio Technology A2451 EpirubicinHCl 5mg $45 2021-12-16 Buy
ApexBio Technology A2451 EpirubicinHCl 10mM(in 1mL DMSO) $64 2021-12-16 Buy
ApexBio Technology A2451 EpirubicinHCl 25mg $180 2021-12-16 Buy

Properties

Melting point :185°C dec.
alpha :D20 +274° (c = 0.01 in methanol)
RTECS :QI9295750
Flash point :443.8℃
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO to 100mM, or in ethanol to 10mM
form :powder
color :red to deep red
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey :MWWSFMDVAYGXBV-UAOJCOQHSA-N
SMILES :C12=C(O)C3=C(C(=O)C4=C(C3=O)C=CC=C4OC)C(O)=C1[C@@]([H])(O[C@H]1O[C@@H](C)[C@H](O)[C@@H](N)C1)C[C@](O)(C(=O)CO)C2.Cl

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Epirubicin is a stereoisomer of the antitumor anthracycline doxorubicin that undergoes β-glucuronidation, which partially detoxifies the dose-limiting side effects that are present with doxorubicin. Compared to doxorubicin, epirubicin is equally cytotoxic to HeLa cells (ID50s = 9 μM). When used either alone or in combination therapies, epirubicin has been shown to demonstrate high rates of complete or partial remission in various cancers including advanced ovary, lymphomas, breast, pancreas, gastric, hepatocellular carcinoma, head and neck tumors, and colorectal.

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