Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> Methotrexate

Methotrexate

Methotrexate price.
  • $8 - $11728
  • Product name: Methotrexate
  • CAS: 59-05-2
  • MF: C20H22N8O5
  • MW: 454.45
  • EINECS:200-413-8
  • MDL Number:MFCD00064370
  • Synonyms:METHOTREXATEFORINJECTION;METHOTREXATE(N-(4-(((2,4-DIAMINO-6-PTERIDINYL)METHYLAMINO)BENZOYL)-L-GLUTAMICACID);4-Amino-N10-methylfolic acid;Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)- (8CI);L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI);L-Methotrexate;Methotrexat-Ebewe;METHOTREXATEC
Price71 Properties Safety Information Description
71 prices
Selected condition：
Brand
  • AccelPharmtech
  • Acrotein
  • Activate Scientific
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AstaTech
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Chemtos
  • Crysdot
  • CSNpharm
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • y0001668
  • 10mg
  • m1000000
  • 20mg
  • 50mg
  • y0000602
  • 2x50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 1mL
  • 2g
  • 5ml
  • 5G
  • 100
  • 10G
  • 25g
  • 100g
  • 5/ G
  • 10mM(in 1mL DMSO)
  • 2*25/ G
  • 10/ G
  • ManufacturerAccelPharmtech
  • Product numberZQ1052
  • Product descriptionMethotrexate 99%
  • Packaging5G
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberZQ1052
  • Product descriptionMethotrexate 99%
  • Packaging10G
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberDM-0144
  • Product descriptionMethotrexate 97%
  • Packaging25g
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS110159-A
  • Product descriptionMethotrexate 99%
  • Packaging250mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS110159-A
  • Product descriptionMethotrexate 99%
  • Packaging1g
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS110159-A
  • Product descriptionMethotrexate 99%
  • Packaging5G
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH023
  • Product descriptionMethotrexate
  • Packaging5g
  • Price$942
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63075
  • Product descriptionMethotrexate
  • Packaging100mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63075
  • Product descriptionMethotrexate
  • Packaging1g
  • Price$603.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045732
  • Product descriptionMETHOTREXATE 95.00%
  • Packaging100MG
  • Price$612.42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045732
  • Product descriptionMETHOTREXATE 95.00%
  • Packaging1G
  • Price$788.52
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045732
  • Product descriptionMETHOTREXATE 95.00%
  • Packaging5G
  • Price$1501.96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4347
  • Product descriptionMethotrexate
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4347
  • Product descriptionMethotrexate
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4347
  • Product descriptionMethotrexate
  • Packaging200mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4347
  • Product descriptionMethotrexate
  • Packaging500mg
  • Price$130
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech ZQ1052 Methotrexate 99% 5G $200 2021-12-16 Buy
AccelPharmtech ZQ1052 Methotrexate 99% 10G $250 2021-12-16 Buy
Acrotein DM-0144 Methotrexate 97% 25g $198 2021-12-16 Buy
Activate Scientific AS110159-A Methotrexate 99% 250mg $34 2021-12-16 Buy
Activate Scientific AS110159-A Methotrexate 99% 1g $68 2021-12-16 Buy
Activate Scientific AS110159-A Methotrexate 99% 5G $176 2021-12-16 Buy
AK Scientific H023 Methotrexate 5g $942 2021-12-16 Buy
Alfa Aesar J63075 Methotrexate 100mg $142 2024-03-01 Buy
Alfa Aesar J63075 Methotrexate 1g $603.65 2024-03-01 Buy
American Custom Chemicals Corporation API0045732 METHOTREXATE 95.00% 100MG $612.42 2021-12-16 Buy
American Custom Chemicals Corporation API0045732 METHOTREXATE 95.00% 1G $788.52 2021-12-16 Buy
American Custom Chemicals Corporation API0045732 METHOTREXATE 95.00% 5G $1501.96 2021-12-16 Buy
ApexBio Technology A4347 Methotrexate 100mg $50 2021-12-16 Buy
ApexBio Technology A4347 Methotrexate 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A4347 Methotrexate 200mg $80 2021-12-16 Buy
ApexBio Technology A4347 Methotrexate 500mg $130 2021-12-16 Buy
Next Last

Properties

Melting point :195°C
Boiling point :561.26°C (rough estimate)
alpha :+17～+24°(D/20℃)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis)
Density :1.4080 (rough estimate)
refractive index :1.6910 (estimate)
Flash point :11℃
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: insoluble
form :powder
pka :pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)
Water Solubility :Insoluble. <0.1 g/100 mL at 19 ºC
Sensitive :Light Sensitive & Hygroscopic
Merck :14,5985
BRN :70669
BCS Class :3
Stability :Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.
InChIKey :FBOZXECLQNJBKD-ZDUSSCGKSA-N
CAS DataBase Reference :59-05-2(CAS DataBase Reference)
NIST Chemistry Reference :Methotrexate(59-05-2)
IARC :3 (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Methotrexate (59-05-2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Methotrexate (MTX) is an analog of folic acid and aminopterin that is used in the treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid and blocking key enzymes in the synthesis of purines and pyrimidines required for cell proliferation. MTX is known to induce adenosine release, which mediates many of its anti-inflammatory effects including the reduction of proinflammatory cytokines. MTX is still considered the gold standard of DMARD (disease-modifying antirheumatic drug) therapy to treat both the immune-inflammatory and joint destructive processes of rheumatoid arthritis.

More related product prices

Benzoyl peroxide Methyl acrylate Kresoxim-methyl L-Glutamic acid Glycine 6-Aminocaproic acid Methylparaben Aminopterin Etoposide 5623-18-7 2410-93-7 945-24-4 6-BROMOMETHYL-PTERIDINE-2,4-DIAMINE HBR 306-67-2 TRICHLORMETHIAZIDE Zinc stearate L-(+)Sodium glutamate (1,4-DIMETHYL-2-PIPERAZINYL)METHANOL

Related product price

Suppliers and manufacturers

Hebei Yanxi Chemical Co., Ltd.
Methotrexate
$800.00 /1000kg
Methotrexate CAS:59-05-2
Hebei Mojin Biotechnology Co., Ltd
Methotrexate
$0.00 /25KG
Methotrexate CAS:59-05-2
Henan Fengda Chemical Co., Ltd
Methotrexate
$1.00 /1000KG
Methotrexate CAS:59-05-2
hebei hongtan Biotechnology Co., Ltd
Methotrexate
$10.00 /5kg
Methotrexate CAS:59-05-2
Shaanxi TNJONE Pharmaceutical Co., Ltd
Methotrexate
$0.00 /1kg
Methotrexate CAS:59-05-2
Hebei Mojin Biotechnology Co.,Ltd
Methotrexate
$0.00 /25kg
Methotrexate CAS:59-05-2
Frapp's ChemicalNFTZ Co., Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.