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1-(6-CHLOROPYRIDIN-3-YL)-2-METHYLPROPAN-1-ONE synthesis

4synthesis methods
-

Yield:244263-45-4 76%

Reaction Conditions:

with Bis<2-(N,N-dimethylamino)aethyl>aether in tetrahydrofuran;cooling;Grignard reaction;

References:

Wang, Xiao-Jun;Zhang, Li;Sun, Xiufeng;Xu, Yibo;Krishnamurthy, Dhileepkumar;Senanayake, Chris H. [Organic Letters,2005,vol. 7,# 25,p. 5593 - 5595]