ChemicalBook CAS DataBase List 1-ISOPROPYL-PIPERIDIN-4-YLAMINE

1-ISOPROPYL-PIPERIDIN-4-YLAMINE synthesis

6synthesis methods

Product Name:1-ISOPROPYL-PIPERIDIN-4-YLAMINE
CAS Number:127285-08-9
Molecular formula:C8H18N2
Molecular Weight:142.24

Carbamic acid, [1-(1-methylethyl)-4-piperidinyl]-, phenylmethyl ester (9CI)

609804-23-1
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127285-08-9
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$18.00/1g

Yield: 98%

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen at 20; under 760.051 Torr; for 20 h;

Steps:

1-Cyclohexylpyrrolidin-3-amine I-6
General procedure: To a solution of compound I-5 (240 mg) in HFIP (8 mL), 10% Pd/C (120 mg) was added and thenthe reaction mixture was stirred under H2 at room temperature and 1atm for 20 h. Then themixture was filtrated and the filtrate was concentrated to give compound I-6 as yellow oil (100 mg,75%).

References:

Zhou, Jie;Ji, Ming;Zhu, Zhixiang;Cao, Ran;Chen, Xiaoguang;Xu, Bailing [European Journal of Medicinal Chemistry,2017,vol. 132,p. 26 - 41] Location in patent:supporting information

534595-37-4 Synthesis

tert-Butyl (1-isopropylpiperidin-4-yl)carbaMate

534595-37-4
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$60.00/100mg

127285-08-9
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References

73874-95-0 Synthesis

73874-95-0
457 suppliers
$10.00/250mg

127285-08-9
107 suppliers
$18.00/1g

References

220394-97-8
77 suppliers
$27.00/250mg

127285-08-9
107 suppliers
$18.00/1g

References

87120-72-7 Synthesis

87120-72-7
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$6.00/1g

127285-08-9
107 suppliers
$18.00/1g

References