ChemicalBook CAS DataBase List 2,4-Diaminobenzenesulfonic acid

2,4-Diaminobenzenesulfonic acid synthesis

10synthesis methods

Product Name:2,4-Diaminobenzenesulfonic acid
CAS Number:88-63-1
Molecular formula:C6H8N2O3S
Molecular Weight:188.2

2,4-Diaminobenzenesulfonic acid is obtained by sulfonating a solution of m-phenylenediamine in 100% sulfuric acid with oleum at 155 ℃, adding water to the sulfonation mixture, desulfonating the resulting disulfonic acids at 140 ℃, and isolating the free acid at 10 ℃; yield 93%. Another process starts from 1-chloro-2,4-dinitrobenzene, which, as an alcoholic solution, is reacted with sodium sulfite solution to form 2,4-dinitrobenzenesulfonic acid, from which the end product is obtained by reduction with iron according to B_E′CHAMP.

108-45-2 Synthesis

108-45-2
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$13.00/25g

88-63-1
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$14.00/100g

Yield:88-63-1 95.96%

Reaction Conditions:

with sulfur trioxide in 1,2-dichloro-ethane at 20 - 60; for 10 h;Solvent;Temperature;

Steps:

6
Weigh 5.40 g (0.05 mol) of m-phenylenediamine into 80 mL of 1,2-dichloroethane, and stir at room temperature to dissolve it;To the above solution, 8.00 g (0.10 mol) of sulfur trioxide was slowly added, and the temperature was raised to 60 ° C, and the reaction was carried out for 10 hours.After completion of the reaction, filtration and drying gave 9.02 g of 2,4-diaminobenzenesulfonic acid, yield: 95.96%.

References:

North University of China;Wang Jianlong;Chen Lizhen;Lian Pengbao;Xiang Yong;Cao Duanlin;Shen Fanfan CN108675946, 2018, A Location in patent:Paragraph 0049-0075

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