ChemicalBook CAS DataBase List 2-Bromoethylamine hydrobromide

2-Bromoethylamine hydrobromide synthesis

3synthesis methods

Product Name:2-Bromoethylamine hydrobromide
CAS Number:2576-47-8
Molecular formula:C2H7Br2N
Molecular Weight:204.89

2-Bromoethylamine hydrobromide was synthesized by bromination of ethanolamine. Drop into hydrobromic acid in the reaction pot, cool, add ethanolamine dropwise under stirring, and finish adding dropwise within half an hour, then steam the hydrobromic acid of 85% of the input quantity (the feed quantity of hydrobromic acid is 8.89 times the weight of ethanolamine) , about 20h steamed. After the concentrated solution is cooled to 70-80°C, it is put into pre-chilled acetone, cooled to below 5°C, and the crystallized 2-bromoethylamine hydrobromide is filtered out. Yield 70%.

141-43-5 Synthesis

141-43-5
858 suppliers
$9.00/10g

2576-47-8
467 suppliers
$8.00/25g

Yield:2576-47-8 99%

Reaction Conditions:

with hydrogen bromide in 5,5-dimethyl-1,3-cyclohexadiene at 0 - 10; for 12 h;

Steps:

1 (1) Synthesis of 2-bromoethylamine hydrobromide (b)
Ethanolamine was added dropwise to 40% hydrobromic acid at a molar ratio of 1:9 at 0-10 ° C, magnetically stirred, the temperature of the reaction system was controlled to not exceed 10 ° C, and the time of dropwise addition of ethanolamine was controlled at 25-30 min. After the addition is completed, it is transferred to the reaction system. The solvent xylene was added, and the water was separated by heating for 12 hours, and the water separation temperature was 135-145 °C. After completion of the water separation, the mixture was cooled, filtered to remove the solvent, and the residue was washed three times with cold acetone to obtain a white crystalline product of 2-bromoethylamine hydrobromide. Yield 99%, purity 99.5%, Melting point 172-174 ° C

References:

Chongqing Normal University;Chongqing Traditional Chinese Medicine Institute;Yang Shanbin;Zhou Shiyang;Yang Dajian CN108658852, 2018, A Location in patent:Paragraph 0024; 0025-0026

FullText

574-98-1
297 suppliers
$5.00/5g

2576-47-8
467 suppliers
$8.00/25g

References

151-56-4 Synthesis

151-56-4
3 suppliers
inquiry

2576-47-8
467 suppliers
$8.00/25g

References

2-Bromoethylamine hydrobromide Related Search:

Triethylamine hydrochloride Pyridine hydrobromide Cyclohexylamine hydrobromide 2-Phenylethylamine hydrochloride Diethylamine hydrochloride 2-BROMOACETAMIDE Bromoacetonitrile Bromoacetic acid Hexahydro-1,3,5-tris(2,3-dibromopropyl)-1,3,5-triazine-2,4,6-trione 4,5-Dibromopyridazin-3-one