(S)-1-methylpyrrolidin-3-yl (R)-2-cyclopentyl-2-hydroxy-2-phenylacetate synthesis
- Product Name:(S)-1-methylpyrrolidin-3-yl (R)-2-cyclopentyl-2-hydroxy-2-phenylacetate
- CAS Number:207856-85-7
- Molecular formula:C18H25NO3
- Molecular Weight:303.4
64471-47-2
20 suppliers
inquiry
104641-59-0
167 suppliers
$5.00/250mg
207856-85-7
18 suppliers
inquiry
Yield:207856-85-7 89.6%
Reaction Conditions:
Stage #1: (R)-α-phenyl-α-cyclopentyl-α-hydroxyacetate methyl ester;(3S)-1-methylpyrrolidin-3-olwith sodium in n-heptane at 110; for 3 h;
Stage #2: with water in n-heptane at 0;
References:
Wu;Wu;Mori;Buchwald;Bodor, Nicholas [Pharmazie,2008,vol. 63,# 3,p. 200 - 209] Location in patent:experimental part
13220-33-2
313 suppliers
$11.00/1g
64471-45-0
21 suppliers
inquiry
616866-21-8
24 suppliers
inquiry
207856-85-7
18 suppliers
inquiry
611-71-2
614 suppliers
$13.00/5g
207856-85-7
18 suppliers
inquiry
894795-19-8
1 suppliers
inquiry
207856-85-7
18 suppliers
inquiry
104612-35-3
45 suppliers
$49.00/250mg
207856-85-7
18 suppliers
inquiry