ChemicalBook CAS DataBase List 3-acetoxy-6-broMoindole

3-acetoxy-6-broMoindole synthesis

8synthesis methods

Product Name:3-acetoxy-6-broMoindole
CAS Number:114306-17-1
Molecular formula:C10H8BrNO2
Molecular Weight:254.08

64-19-7 Synthesis

64-19-7
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$10.00/25ML

372077-73-1 Synthesis

372077-73-1
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114306-17-1
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$125.00/100mg

Yield: 254 mg

Reaction Conditions:

with silver(I) acetate at 90; for 3 h;

Steps:

3-Acetoxy-6-bromoindole (3)
Silver acetate (341 mg,2.04 mmol) was added to a solution of monomer 2 in acetic acid(8 mL). After stirring for 3 h at 90 C, the mixture was cooled toroom temperature and filtered. The filtrate was evaporated todryness under reduced pressure. The residue was chromatographedon silica gel with dichloromethane as eluent to affordproduct 3 (yield: 254 mg, 63.0%). 1H NMR (CDCl3, 600 MHz): 7.97 (s,1H), 7.69 (d, 1H), 7.33 (d, 1H), 7.29 (m, 1H), 7.17 (m, 1H), 2.36 (s, 9H);13C NMR (CDCl3, 600 MHz): 168.65, 131.70, 129.82, 125.78, 121.61,120.14, 114.64, 113.17, 112.90, 20.93.

References:

Liu, Chunchen;Xu, Wenzhan;Xue, Qifan;Cai, Ping;Ying, Lei;Huang, Fei;Cao, Yong [Dyes and Pigments,2016,vol. 125,p. 54 - 63]