3-N-Boc-amino-azetidine synthesis

Yield:91188-13-5 100%

Reaction Conditions:

with hydrogen;palladium 10% on activated carbon in ethanol at 20; for 2 h;

Steps:

1.1.A
A mixture of (113 mg, 0.33 mmol) and 10% Pd/C (88 mg) in ethanol (3 ml) was stirred under hydrogen atmosphere at rt for 2 h. The reaction mixture was filtered and evaporated to give XXA (63 mg) as a white solid.

References:

Bisacchi, Gregory S.;Sutton, James C.;Slusarchyk, William A.;Treuner, Uwe;Zhao, Guohua US2004/147502, 2004, A1 Location in patent:Page/Page column 23; 25

FullText