ChemicalBook CAS DataBase List 3-Chloro-benzo[d]isothiazole 1,1-dioxide

3-Chloro-benzo[d]isothiazole 1,1-dioxide synthesis

3synthesis methods

Product Name:3-Chloro-benzo[d]isothiazole 1,1-dioxide
CAS Number:567-19-1
Molecular formula:C7H4ClNO2S
Molecular Weight:201.63

3-Chloro-benzo[d]isothiazole 1,1-dioxide was prepared by reacting saccharin with thionyl chloride in prestence of DMF as catalyst.

81-07-2
432 suppliers
$13.98/25G

3-Chloro-benzo[d]isothiazole 1,1-dioxide

567-19-1
57 suppliers
$65.00/50mg

Yield: 99%

Reaction Conditions:

with thionyl chloride;N,N-dimethyl-formamide in 1,4-dioxane for 24 h;Reflux;

Steps:

1.A Step A: 3-chloro-1,2-benzothiazole-1,1-dioxide
A mixture of saccharin (70.00 g; 382.13 mmol; 1.00 eq.), thionyl chloride (41.58 ml; 573.19 mmol; 1.50 eq.) and a catalytic amount of DMF (2.10 ml) in 1,4-dioxane (350 ml) was heated for 24h under reflux. The reaction mixture was concentrated, co-evaporated 4 times with toluene (200 ml) and dried to give 3-chloro-1,2-benzothiazole-1,1-dioxide (77.00 g; 99 %), used without further purification

References:

Eng Bang Tiba;Ba Seu-ma-tin;Kon Tal-sil-bi-e;Ju Ni-en-jang---ru-i-seu;Ma Sa-reu-di-e-reu-keu-ri-seu-tin;Mon Tal-be-ti-keu-ri-seu-chan;Su Deu-an-ne KR2019/137803, 2019, A Location in patent:Paragraph 0384-0386

5669-05-6
5 suppliers
inquiry

567-19-1
57 suppliers
$65.00/50mg

References

7719-09-7
391 suppliers
$15.00/10g

81-07-2
432 suppliers
$13.98/25G

567-19-1
57 suppliers
$65.00/50mg

References

3-Chloro-benzo[d]isothiazole 1,1-dioxide Related Search:

3-Chloro-1,2-benzisothiazole