ChemicalBook CAS DataBase List Cyclopropyl 4-methoxyphenyl ketone

Cyclopropyl 4-methoxyphenyl ketone synthesis

12synthesis methods

Product Name:Cyclopropyl 4-methoxyphenyl ketone
CAS Number:7152-03-6
Molecular formula:C11H12O2
Molecular Weight:176.21

4023-34-1 Synthesis

4023-34-1
355 suppliers
$12.00/5g

100-66-3 Synthesis

100-66-3
506 suppliers
$10.00/5G

7152-03-6
89 suppliers
$15.00/5 g

Yield:7152-03-6 83%

Reaction Conditions:

with copper(II) ferrite in 1,2-dichloro-ethane at 35 - 38; for 18 h;Friedel-Crafts Acylation;

Steps:

General procedure: The FC acylation of various benzenes with acid chlorides was carried out in the presence of magnetic nano CuFe2O4 (particle size = 50 nm) by using one of the reaction condition (A-D) given below. Condition A: Anisole/arene (1 mmol), acid chloride (1.2 mmol), nano CuFe2O4 (20 mol %), 1,2-DCE (2 mL), 80 C and 24 h. Condition B: Anisole/arene (1 mmol), acid chloride (1.2 mmol), nano CuFe2O4 (20 mol %), 1,2-DCE (2 mL), rt (35-38 C) and 18 h. Condition C: Neat reaction, anisole/arene (3.3 mmol), acid chloride (1.2 mmol), nano CuFe2O4 (20 mol %), rt (35-38 C) and 18 h. Condition D: Neat reaction, arene/anisole (3.3 mmol), acid chloride (1.2 mmol), nano CuFe2O4 (20 mol %), 80 C and 18 h.

References:

Parella, Ramarao;Naveen;Kumar, Amit;Babu, Srinivasarao Arulananda [Tetrahedron Letters,2013,vol. 54,# 13,p. 1738 - 1742]

FullText

40877-19-8 Synthesis