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ChemicalBook CAS DataBase List (R)-(-)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL

(R)-(-)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL synthesis

9synthesis methods
-

Yield: 95%

Reaction Conditions:

Stage #1:1,2-Dihydronaphthalene with benzo[1,3,2]dioxaborole;rhodium complex 2 in toluene at 20; for 2 h;Addition;Hydroboration;
Stage #2: with sodium hydroxide;water;dihydrogen peroxide in toluene at 20; for 2 h;Oxidation;

References:

Doucet, Henri;Fernandez, Elena;Layzell, Timothy P.;Brown, John M. [Chemistry - A European Journal,1999,vol. 5,# 4,p. 1320 - 1330]

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