| Identification | More | [Name]
Dibenzofuran | [CAS]
132-64-9 | [Synonyms]
BIPHENYLENE OXIDE
DIBENZO[B,D]FURAN
DIBENZOFURAN
DIPHENYLENE OXIDE
(1,1’-biphenyl)-2,2’-diyloxide
[1,1'-Biphenyl]-2,2'-diyl oxide
2,2’-biphenyleneoxide
2,2’-biphenylyleneoxide
2,2'-Biphenylene oxide
2,2'-Biphenylylene oxide
Dibenzofurane
dibenzol(b,d)furan
Dibenzo[b,d]furan (purity)
DIBENZOFURAN, 100MG, NEAT
DIBENZOFURAN, 1X1ML, MEOH, 5000UG/ML
DIBENZOFURAN, 1X1ML, CH2CL2, 200UG/ML
DIBENZOFURAN, 99+%
73661, Dibenzo[b,d]furan (purity)
DIBENZOFURAN OEKANAL, 250 MG
DIBENZOFURAN, TECH., 90% | [EINECS(EC#)]
205-071-3 | [Molecular Formula]
C12H8O | [MDL Number]
MFCD00004968 | [Molecular Weight]
168.19 | [MOL File]
132-64-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Dibenzofuran is a white crystalline powder. | [Melting point ]
80-82 °C (lit.) | [Boiling point ]
154-155 °C/20 mmHg (lit.) | [density ]
1,3 g/cm3 | [vapor pressure ]
2.48 x 10-3 mmHg at 25 °C (Chirico et al., 1990) | [refractive index ]
1.6480 | [Fp ]
130 °C
| [storage temp. ]
2-8°C | [solubility ]
Insoluble in wate(<1 mg/mL). Soluble in nonpolar organic solvents. | [form ]
neat | [color ]
White to Almost white | [Water Solubility ]
<0.1 g/100 mL at 20 ºC | [Detection Methods]
GC,NMR | [BRN ]
121100 | [Henry's Law Constant]
5.82 x 10-5 atm?m3/mol at 25 °C (approximate - calculated from water solubility and vapor pressure) | [Dielectric constant]
3.0（100℃） | [InChIKey]
TXCDCPKCNAJMEE-UHFFFAOYSA-N | [CAS DataBase Reference]
132-64-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Dibenzofuran(132-64-9) | [EPA Substance Registry System]
132-64-9(EPA Substance) |
| Questions And Answer | Back Directory | [Chemical reactivity]
Chemical reactivity is analogous to benzo[b]furan, especially electrophilic substitution reactions such as nitration,
halogenation, sulfonation, acylation, and alkylation reactions. The preferred positions are 2 and 2,8, while nitration
takes place at the 3- and 3,8-positions depending on the electrophilicity of the functionality. |
| Safety Data | Back Directory | [Hazard Codes ]
N,Xn,T,F | [Risk Statements ]
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R22:Harmful if swallowed.
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R63:Possible risk of harm to the unborn child.
R43:May cause sensitization by skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin .
R45:May cause cancer. | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S29:Do not empty into drains .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves .
S16:Keep away from sources of ignition-No smoking .
S7:Keep container tightly closed .
S7/9:Keep container tightly closed and in a well-ventilated place .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S53:Avoid exposure-obtain special instruction before use . | [RIDADR ]
UN3077 | [WGK Germany ]
3
| [RTECS ]
HP4430000
| [TSCA ]
Yes | [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
29329995 | [Hazardous Substances Data]
132-64-9(Hazardous Substances Data) | [Toxicity]
Heitmuller et al. (1981) reported a NOEC of 1.0 ppm. |
| Hazard Information | Back Directory | [General Description]
Colorless white crystalline solid. | [Reactivity Profile]
DIBENZOFURAN(132-64-9) is sensitive to prolonged exposure to light . | [Air & Water Reactions]
Insoluble in water. | [Potential Exposure]
This material is used as an insecticide
and in organic synthesis to make other chemicals. It is
derived from coal tar creosote. | [Fire Hazard]
Flash point data for this chemical are not available. DIBENZOFURAN is probably combustible. | [First aid]
Skin Contact:
Flood all areas of body that
have contacted the substance with water. Don’t wait to
remove contaminated clothing; do it under the water
stream. Use soap to help assure removal. Isolate contami-
nated clothing when removed to prevent contact by others.
Eye Contact: Remove any contact lenses at once. Flush
eyes well with copious quantities of water or normal saline
for at least 20 30 minutes. Seek medical attention.
Inhalation: Leave contaminated area immediately; breathe
fresh air. Proper respiratory protection must be supplied to
any rescuers. If coughing, difficult breathing or any other
symptoms develop, seek medical attention at once, even if symptoms develop many hours after exposure. Ingestion:
If convulsions are not present, give a glass or two of water
or milk to dilute the substance. Assure that the person’s
airway is unobstructed and contact a hospital or poison
center immediately for advice on whether or not to induce
vomiting. | [Shipping]
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous
hazardous material, Technical Name Required. | [Incompatibilities]
This material is used as an insecticide
and in organic synthesis to make other chemicals. It is
derived from coal tar creosote. | [Description]
Dioxins and furans, two well-known environmental pollutants,
are extremely toxic to humans and many other species. Dibenzofurans
are released into the air from combustion sources,
and are listed as pollutants of concern due to its persistence
in the environment, potential to bioaccumulate, and toxicity
to humans and the environment. These compounds, when
adsorbed on soils or other substrates, are highly persistent
under normal environmental conditions. The Office of Environmental
Health Hazard Assessment reviews risk assessments
submitted under the Air Toxics ‘Hot Spots’ Program (AB 2588)
in which chlorinated dibenzo-p-dioxins and dibenzofurans are
listed. Chlorinated dibenzofurans were calculated as total
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) equivalents in the
AB 2588 risk assessments. Dibenzofuran is cited in the Clean Air
Act 1990 Amendments – Hazardous Air Pollutants as a volatile
hazardous air pollutant of potential concern. The Superfund
Amendment Reauthorization Act Section 110 placed dibenzofuran
on the revised Agency for Toxic Substances and Disease
Registry priority list of hazardous substances to be the subject
of a toxicological profile. Dibenzofuran is also listed in the
Massachusetts Substance List for Right to Know Law, the New
Jersey Department of Health Hazard Right to Know Program
Hazardous Substance List, the Pennsylvania Department
of Labor and Industry Hazardous Substance List, and the
California’s Air Toxics ‘Hot Spots’ List (Assembly Bill 2588). | [Chemical Properties]
Dibenzofuran is a white crystalline powder. | [Chemical Properties]
white to light yellow crystal powde | [Waste Disposal]
In accordance with
40CFR165, follow recommendations for the disposal of
pesticides and pesticide containers. Must be disposed prop-
erly by following package label directions or by contacting
your local or federal environmental control agency, or by
contacting your regional EPA office. | [Physical properties]
Colorless crystals having a creosote-like odor. The least detectable odor threshold concentration in
water at 60 °C was 2 μg/L (Alexander et al., 1982). | [Uses]
Applications for GC (Gas Chromatography) and LC (Liquid Chromatography) Analysis. Dibenzofuran as the model substrate in culture procedures. | [Uses]
Dibenzofuran is an industrial chemical or by-product, and is
used as an insecticide, in the production of PVC, industrial
bleaching and incineration. | [Uses]
Research chemical. Derived from industrial and experimental coal gasification operations
where the maximum concentration detected in coal gas tar streams was 12 mg/m3 (Cleland, 1981). | [Definition]
ChEBI: A mancude organic heterotricyclic parent that consists of a furan ring flanked by two benzene rings ortho-fused across the 2,3- and 4,5-positions. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 81, p. 487, 1959 DOI: 10.1021/ja01511a056
The Journal of Organic Chemistry, 40, p. 1365, 1975 DOI: 10.1021/jo00897a048 | [Source]
Based on laboratory analysis of 7 coal tar samples, dibenzofuran concentrations ranged
from 170 to 4,000 ppm (EPRI, 1990).
Schauer et al. (1999) reported dibenzofuran in diesel fuel at a concentration of 29 μg/g and in a
diesel-powered medium-duty truck exhaust at an emission rate of 28.7 μg/km.
Gas-phase tailpipe emission rates from gasoline-powered automobiles with and without
catalytic converters were 5.5 and 42.2 μg/km, respectively (Schauer et al., 2002). | [Environmental Fate]
Biological. Dibenzofuran was oxidized by salicylate-induced cells of Pseudomonas sp. strain
9816/11 and isopropyl-β-D-thiogalactopyranoside-induced cells of Escherichia coli JM109(DE3)
(pDTG141) to (1R,2S)-cis-1,2-dihydroxy-1,2-dihydrodibenzofuran (60–70% yield) and (3S,4R)-
cis-3,4-dihydroxy-3,4-dihydrodibenzofuran (30–40% yield) (Resnick and Gibson, 1996).
Soil. The estimated half-lives of dibenzofuran in soil under aerobic and anaerobic conditions
were 7 to 28 and 28 to 112 d, respectively (Lee et al., 1984).
Groundwater. Based on aerobic acclimated and unacclimated groundwater die away test data,
the estimated half-life of dibenzofuran in groundwater ranged from 8.54 to 34.9 d (Lee et al.,
1984).
Photolytic. The estimated half-life for the reaction of dibenzofuran with OH radicals in the
atmosphere ranged from 1.9 to 19 h (Atkinson, 1987).
Chemical/Physical. It was suggested that the chlorination of dibenzofuran in tap water
accounted for the presence of chlorodibenzofuran (Shiraishi et al., 1985).
Dibenzofuran will not hydrolyze because it has no hydrolyzable functional group (Kollig,
1995). | [storage]
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. | [Purification Methods]
Dissolve dibenzofuran in diethyl ether, then shake it with two portions of aqueous NaOH (2M), wash it with water, separate and dry (MgSO4) it. After evaporating the ether, dibenzofuran is crystallised from aqueous 80% EtOH and then dried under vacuum. [Cass et al. J Chem Soc 1406 1958.] High purity material is obtained by zone refining. [Beilstein 17 V 234.] | [Toxicity evaluation]
Dibenzofuran is a white crystalline solid. It is not soluble in
water, but soluble in organic solvents like alcohol, acetone,
ether, benzene, and acetic acid. Its boiling point is 287°C,
melting point is 86°C, and specific gravity is 1.0886. Its octanol/
water partition coefficient is 4.12.
Presence of dibenzofuran in coal tar, oil and its uses may
result in its release to the environment through various waste
streams. It has very low to no mobility in soil and degrades in
soil. It dissolves in water as well as volatilizes. As a gas phase in
the atmosphere, it reacts with photochemically produced
hydroxy radicals. It is biodegraded rapidly at contaminated
sites by the microorganisms present; otherwise its biodegradation
is relatively slow. It adsorbs very strongly to sediment
and particulate matter in the water column. It has a potential to
bioconcentrate in aquatic organisms. |
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