| Identification | More | [Name]
Ethyl 5-nitroindole-2-carboxylate | [CAS]
16732-57-3 | [Synonyms]
5-NITROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER
ETHYL 5-NITRO-1H-INDOLE-2-CARBOXYLATE
ETHYL 5-NITRO-2-CARBOXYLATE
ETHYL 5-NITROINDOLE-2-CARBOXYLATE
LABOTEST-BB LT00441291
OXALIC ACID MONO-(N-METHYL)-AMIDE
Ethyl 5-Nitro Indole-2-Carbonate
5-Nitroindole-2-Carboxylic
5-Nitroindole-2-carboxylate
Ethyl 5-nitro-1H-indole-2-carboxylate ,98% | [Molecular Formula]
C11H10N2O4 | [MDL Number]
MFCD06245498 | [Molecular Weight]
234.21 | [MOL File]
16732-57-3.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow to brown powder | [Melting point ]
220-225 °C
| [Boiling point ]
376.52°C (rough estimate) | [density ]
1.3240 (rough estimate) | [refractive index ]
1.5300 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
Powder | [pka]
13.26±0.30(Predicted) | [color ]
Yellow to brown | [Water Solubility ]
negligible | [Detection Methods]
HPLC,NMR,MS | [CAS DataBase Reference]
16732-57-3(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
Ethyl 5-Nitroindole-2-carboxylate is used as a reagent in the synthesis of indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. Ethyl 5-Nitroindole-2-carboxylate is also a useful synthetic intermediate in the synthesis of Delavirdine which is a bisheteroarylpiperazine (BHAP) reverse transcriptase inhibitor. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29349990 |
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