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1707-77-3

1707-77-3 Structure

1707-77-3 Structure
IdentificationMore
[Name]

1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
[CAS]

1707-77-3
[Synonyms]

1,2:5,6-bis-o-(1-methylethylidene)-d-mannitol
1,2:5,6-BIS-O-(1-METHYLETHYLIDENE)-D-MARNITOL
1,2,5,6-DI-O-ISOPROPYLIDENE-D-MANNITOL
1,2:5,6-DI-O-ISOPROPYLIDENE-D-MANNITOL
1,2:5,6-ISOPROPYLIDENE-D-MANNITOL
1,2-bis(2,2-dimethyl-1,3-dioxolan-4-yl)-1,2-ethanediol
DIACETONE-D-MAN
DIACETONE-D-MANNITOL
D-MANNITOL DIACETONIDE
1,2,5,6-Diisopropylidene-D-mannitol
1,2-5,6-Diacetone D-mannitol
Diisopropylidene mannitol
Mannitol, 1,2:5,6-di-O-isopropylidene-, D
1,2,5,6-DI-Isopopylidene-D-Mannitol
Isopropylidene-D-Mannitol
(2,2,2',2'-TETRAMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-5-YL)-METHANOL
D-Mannitol, 1,2:5,6-bis-O-(1-methylethylidene)-
1 2:5 6-DI-O-ISOPROPYLIDENE-D-MANNITOL 98%
1,2:5,6-DI-O-ISOPROPYLIDINE-D-MANNITOL
(1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolane-4-yl]-1,2-ethanediol
[EINECS(EC#)]

216-954-8
[Molecular Formula]

C12H22O6
[MDL Number]

MFCD00003211
[Molecular Weight]

262.3
[MOL File]

1707-77-3.mol
Chemical PropertiesBack Directory
[Melting point ]

120-122 °C(lit.)
[alpha ]

6 º (c=5, Chloroform)
[Boiling point ]

382.0±32.0 °C(Predicted)
[density ]

1.175±0.06 g/cm3(Predicted)
[refractive index ]

6.5 ° (C=8, CHCl3)
[storage temp. ]

2-8°C
[solubility ]

methanol: 100 mg/mL, clear, colorless
[form ]

Crystalline Powder
[pka]

12.98±0.20(Predicted)
[color ]

White
[optical activity]

[α]/D +6.0±1.0°, c = 5 in chloroform
[BRN ]

83765
[InChIKey]

ODYBCPSCYHAGHA-ZYUZMQFOSA-N
[CAS DataBase Reference]

1707-77-3(CAS DataBase Reference)
[NIST Chemistry Reference]

D-Mannitol, 1,2:5,6-bis-o-(1-methylethylidene)-(1707-77-3)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37:Wear suitable protective clothing and gloves .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[F ]

10-21
[HS Code ]

29329990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

D-Mannitol, 1,2:5,6-bis-O-(1-methylethylidene)-, diacetate (9CI)-->2-Methoxypropene-->Acetone-->2,2-Dimethoxypropane-->D-Mannitol
[Preparation Products]

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol-->(S)-(+)-(2,2-DIMETHYL-[1,3]-DIOXOLAN-4-YL)-METHYLAMINE-->(S)-4-BENZYLOXYMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE-->D-Glyceraldehyde-->(S)-4,5-ISOPROPYLIDENE-2-PENTENYLBROMIDE
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Nebivolol intermediate.
[Purification Methods]

Although quite soluble in H2O, it gives a purer product when crystallised from this solvent, forming needles [Baer J Am Chem Soc 67 338 1945, NMR: Curtis et al. J Chem Soc, Perkin Trans 1 1756 1977]. [Beilstein 19/11 V 589.]
Spectrum DetailBack Directory
[Spectrum Detail]

1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol(1707-77-3)IR
1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol(1707-77-3)FT-IR
1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol(1707-77-3)Raman
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

1,2:5,6-Di-O-isopropylidene-D-mannitol(1707-77-3)
[Sigma Aldrich]

1707-77-3(sigmaaldrich)
[TCI AMERICA]

1,2:5,6-Di-O-isopropylidene-D-mannitol,>95.0%(GC)(1707-77-3)
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