| Identification | More | [Name]
2-Bromo-4-(trifluoromethyl)pyridine | [CAS]
175205-81-9 | [Synonyms]
2-BROMO-4-(TRIFLUOROMETHYL)PYRIDINE | [EINECS(EC#)]
672-057-5 | [Molecular Formula]
C6H3BrF3N | [MDL Number]
MFCD00153085 | [Molecular Weight]
225.99 | [MOL File]
175205-81-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
-21--20 °C | [Boiling point ]
84-85 °C/14 mmHg | [density ]
1.827 g/mL at 25 °C
| [refractive index ]
n20/D 1.478
| [Fp ]
164 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [pka]
-1.57±0.10(Predicted) | [InChIKey]
WZVHLUMAQLUNTJ-UHFFFAOYSA-N | [CAS DataBase Reference]
175205-81-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [Risk Statements ]
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R37/38:Irritating to respiratory system and skin .
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S37:Wear suitable gloves . | [RIDADR ]
UN 2810 6.1/PG 3
| [WGK Germany ]
3
| [Hazard Note ]
Toxic/Irritant | [HazardClass ]
IRRITANT | [PackingGroup ]
Ⅲ |
| Hazard Information | Back Directory | [Uses]
Regioselective deprotonation at C-3 with LDA followed by trapping with carbon dioxide provides the correspondin nicotinic acid. | [Uses]
2-Bromo-4-(trifluoromethyl)pyridine in used in the preparation of pyrazolopyridines as kinase LRRK2 inhibitors for treating and preventing cancer and neurodegenerative diseases. |
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