| Identification | More | [Name]
2-PIPERIDYLMETHYLAMINE | [CAS]
22990-77-8 | [Synonyms]
2-(AMINOMETHYL)-1-PIPERIDINE
2-AMINOMETHYL PIPERIDINE
2AMPPR
2-PIPERIDINEMETHANAMINE
2-PIPERIDYLMETHYLAMINE
piperidine-2-methylamine
C-PIPERIDIN-2-YL-METHYLAMINE
2-(Aminomethyl)
1-(Piperidin-2-yl)methylamine
1-piperidin-2-ylmethanamine
2-AMINOMETHYL PIPERIDINE 99%
Piperidine-2-methanamine | [EINECS(EC#)]
245-371-1 | [Molecular Formula]
C6H14N2 | [MDL Number]
MFCD03428050 | [Molecular Weight]
114.19 | [MOL File]
22990-77-8.mol |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
2735 | [WGK Germany ]
2 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Uses]
Reactant for reversible aminal formation
Reactant for synthesis of:
- Annulated N-heterocyclic carbene ligands
- M3 Muscarinic receptor antagonists
- Selective 5-ht5A receptor antagonists
- Ternary platinum(II) complexes
| [Uses]
2-Piperidinemethanamine is used in the synthesis of compounds exhibiting anti-osteoclast and anti-osteoblast activity. It also is used in the synthesis of potent antibacterial.
| [Purification Methods]
Dry (over Na2SO4) and distil the piperidine under vacuum from KOH. It has been purified via the Reinekate salt (m 173-174o) and its dipicrate salt (m 201o, from H2O). [Norton et al. J Am Chem Soc 68 1330 1946, Mortimer Aust J Chem 11 84 1958, Augustine J Am Chem Soc 81 4667 1959, Beilstein 22 III/IV 3765.] |
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