| Identification | More | [Name]
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE | [CAS]
28480-70-8 | [Synonyms]
2-ACETYL-4-CHLORO-5-METHYLPHENOL
4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE
5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
5'-Chooro-2'-Hydroxy-4'-Methylacetophenone
1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE
5'-Chloro-2'-hydroxy-4'-methylacetophenone 98%
5'-Chloro-2'-hydroxy-4'-methylacetophenone >
Ethanone, 1-(5-chloro-2-hydroxy-4-methylphenyl)-
JRH-01005, 1-(5-Chloro-2-hydroxy-4-methylphenyl)ethanone, 97%
4-Acetyl-2-chloro-5-hydroxytoluene
2-Acetyl-4-chloro-5-methylphenol | [Molecular Formula]
C9H9ClO2 | [MDL Number]
MFCD00191920 | [Molecular Weight]
184.62 | [MOL File]
28480-70-8.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
2914.50.3000 |
| Hazard Information | Back Directory | [Uses]
5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:
- chalcones, required for the synthesis of novel pyrazoline derivatives
- 5′-chloro-2′-hydroxy-4′-methyl-3-(2′′-thienyl)acrylophenone
- 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)
| [Preparation]
Preparation by reaction of acetic acid on 4-chloro-3- methylphenol with boron trifluoride at 70–100° (80–85%). | [General Description]
5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone. |
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